CAJ | 학술논문

目的研究糖尿病与乳腺癌患者生命质量的关系,为糖尿病和乳腺癌患者生命质量的综合改善提供依据.方法 2013年4月至7月在上海进行横断面研究,3 344例女性社区乳腺癌患者接受问卷调查,调查内容包括社会人口学情况、肿瘤的诊断和治疗情况、糖尿病患病情况等,以欧洲癌症研究与治疗组织QOL量表C30(EORTC QLQ-C30)中文版和癌症治疗功能评估量表(FACT-G)中文版分析受试者的生命质量.比较患和未患糖尿病的乳腺癌患者生命质量的组间差异.结果在所有被调查的乳腺癌患者中同时患有糖尿病者为14.38％.对于EORTC QLQ-C30量表,患糖尿病者的躯体功能、角色功能、认知功能、情绪功能、社会功能及总体健康状况得分均显著低于未患糖尿病者的相应得分(P＜0.05),而在疲倦、恶心呕吐、疼痛、气促、失眠、食欲丧失、便秘等生理及症状维度以及经济困难领域患糖尿病者得分均高于未患糖尿病者,且大部分均有显著性差异.对于FACT-G量表,未患糖尿病者的生理状况、社会状况、情感状况、功能状况4个维度得分以及FACT-G总分均显著高于糖尿病患者的相应得分(P＜0.05).结论糖尿病影响乳腺癌患者的生命质量,应采取慢性病综合管理措施以提高糖尿病和乳腺癌患者的生命质量.
목적 연구당뇨병여유선암환자생명질량적관계,위당뇨병화유선암환자생명질량적종합개선제공의거.방법 2013년4월지7월재상해진행횡단면연구,3 344례녀성사구유선암환자접수문권조사,조사내용포괄사회인구학정황、종류적진단화치료정황、당뇨병환병정황등,이구주암증연구여치료조직QOL량표C30(EORTC QLQ-C30)중문판화암증치료공능평고량표(FACT-G)중문판분석수시자적생명질량.비교환화미환당뇨병적유선암환자생명질량적조간차이.결과 재소유피조사적유선암환자중동시환유당뇨병자위14.38％.대우EORTC QLQ-C30량표,환당뇨병자적구체공능、각색공능、인지공능、정서공능、사회공능급총체건강상황득분균현저저우미환당뇨병자적상응득분(P＜0.05),이재피권、악심구토、동통、기촉、실면、식욕상실、편비등생리급증상유도이급경제곤난영역환당뇨병자득분균고우미환당뇨병자,차대부분균유현저성차이.대우FACT-G량표,미환당뇨병자적생리상황、사회상황、정감상황、공능상황4개유도득분이급FACT-G총분균현저고우당뇨병환자적상응득분(P＜0.05).결론 당뇨병영향유선암환자적생명질량,응채취만성병종합관리조시이제고당뇨병화유선암환자적생명질량.
Objective To investigate the impact of diabetes on quality of life in breast cancer patients.Methods A cross-sectional study was conducted among 3 344 community patients suffering from breast cancer during April to July 2013,in Shanghai.Data were collected using a questionnaire,which included socio-demographic situation,diagnosis,and treatment of cancer,as well as diabetes mellitus.European Organization for Research and Treatment of Cancer QOL Questionnaire-C30 (EORTC QLQ-C30) Simplified Chinese Version and Functional Assessment of Cancer Therapy (FACT-G) Simplified Chinese Version were used to investigate the quality of life in the patients.The quality of life scores in breast cancer patients with and without diabetes were compared.Results The prevalence of diabetes was 14.38％ in the patients with breast cancer.Breast cancer patients without diabetes reported significantly higher EORTC QLQ-C30 scores in physical functioning,role functioning,cognitive functioning,emotional functioning,social functioning,global health,lower EORTC QLQ-C30 scores in fatigue,pain,dyspnoea,insomnia,appetite loss,constipation,diarrhoea,and higher FACT-G scores in physical well-being,social/family well-being,emotional well-being,functional well-being,compared with the patients with diabetes (P ＜ 0.05).Conclusions Diabetes mellitus affects the quality of life in patients with breast cancer.Integrated measures for chronic disease management should be taken to improve the quality of life in patients with breast cancer as well as diabetes mellitus.