CAJ | 학술논문

目的采用CT测量5岁以下儿童呼气末、吸气末肺组织的平均密度值.方法选取2010年1月至2012年3月在我院因外伤等疾病进行胸部CT扫描的正常肺患儿60例.通过随机数字表法分为吸气末扫描组与呼气末扫描组进行通气控制CT扫描,每组30例.获取胸部吸气末、呼气末CT图像.胸部CT图像中选取主动脉弓上2 cm、隆突下1 cm、膈上2cm3个层面肺组织的腹侧、背侧、外侧、内侧、中心测量肺CT值.计算左肺、右肺以及全肺的平均密度值.对单侧肺吸气末、呼气末各测量区域肺密度值的变化采用单因素方差分析,各测量区域间肺密度值变化两两比较采用LSD法.结果吸气末左肺、右肺及全肺对应的肺密度值均为(-766±56)HU,呼气末相应的值分别为(-625±86)、(-647±85)、(-636±86)HU.吸气末,左肺腹侧、背侧、外侧、内侧、中心肺密度值分别为(-798±63)、(-733±68)、(-767±64)、(-754±65)、(-775±63)HU,右肺分别为(-796±70)、(-736±65)、(-769±64)、(-754±62)、(-776±59)HU;呼气末,左肺上述5个部位肺密度值分别为(-692±91)、(-555±116)、(-639±91)、(-598±103)、(-640±98)HU,右肺分别为(-712±90)、(-575±121)、(-657±90)、(-619±95)、(-670±87)HU,双肺5个测量部位在吸气末和呼气末肺密度值差异均有统计学意义(F值分别为12.55、11.29、23.31、25.47,P值均＜0.01).5个测量部位中,背侧肺密度平均值最高,腹侧最低,其余从高到低分别为内侧、外侧、中心.结论本研究测量得到5岁以下儿童呼气末、吸气末肺组织的密度值,可为临床工作提供参考.
목적 채용CT측량5세이하인동호기말、흡기말폐조직적평균밀도치.방법 선취2010년1월지2012년3월재아원인외상등질병진행흉부CT소묘적정상폐환인60례.통과수궤수자표법분위흡기말소묘조여호기말소묘조진행통기공제CT소묘,매조30례.획취흉부흡기말、호기말CT도상.흉부CT도상중선취주동맥궁상2 cm、륭돌하1 cm、격상2cm3개층면폐조직적복측、배측、외측、내측、중심측량폐CT치.계산좌폐、우폐이급전폐적평균밀도치.대단측폐흡기말、호기말각측량구역폐밀도치적변화채용단인소방차분석,각측량구역간폐밀도치변화량량비교채용LSD법.결과 흡기말좌폐、우폐급전폐대응적폐밀도치균위(-766±56)HU,호기말상응적치분별위(-625±86)、(-647±85)、(-636±86)HU.흡기말,좌폐복측、배측、외측、내측、중심폐밀도치분별위(-798±63)、(-733±68)、(-767±64)、(-754±65)、(-775±63)HU,우폐분별위(-796±70)、(-736±65)、(-769±64)、(-754±62)、(-776±59)HU;호기말,좌폐상술5개부위폐밀도치분별위(-692±91)、(-555±116)、(-639±91)、(-598±103)、(-640±98)HU,우폐분별위(-712±90)、(-575±121)、(-657±90)、(-619±95)、(-670±87)HU,쌍폐5개측량부위재흡기말화호기말폐밀도치차이균유통계학의의(F치분별위12.55、11.29、23.31、25.47,P치균＜0.01).5개측량부위중,배측폐밀도평균치최고,복측최저,기여종고도저분별위내측、외측、중심.결론 본연구측량득도5세이하인동호기말、흡기말폐조직적밀도치,가위림상공작제공삼고.
Objective To measure the average value of CT lung density at the phase of end inspiration and end expiration in children under 5 years.Methods Sixty patients with normal lungs who underwent chest CT for reasons caused by trauma etc.in our institute from January 2010 to March 2012 were enrolled to the study.All of the patients were divided into end inspiration group and end expiration group through random number table.CT images of the phase of end inspiration and end expiration were taken.Three levels of CT images were chosen to measure the lung density,which were 2 cm above the arch,1 cm below the carina and 2 cm above diaphragm.Lung density was measured at anterior,posterior,lateral,medial and central of the images at each level in each lung.The average lung density of each and entire lung were respectively calculated.The influence of phase,level,location was quantified using analysis of variance methods and LSD method.Results The average lung density at end inspiration was (-766 ±56)HU for the left,right and both lung.At end expiration,the average lung density of the left,right and both lungs was (-625 ± 86),(-647 ± 85) and (-636 ± 86) HU respectively.The average densities at anterior,posterior,lateral,medial and central of the left lung at end inspiration were (-798±63),(-733±68),(-767±64),(-754 ±65),(-775 ±63)HU respectively.The average densities at anterior,posterior,lateral,medial and central of the right lung were (-796 ± 70),(-736 ± 65),(-769 ± 64),(-754 ± 62),(-776-± 59) HU respectively.At end expiration phase,the average densities at anterior,posterior,lateral,medial and central of the left lung were (-692±91),(-555±116),(-639±91),(-598±103),(-640±98) HU respectively.The average densities at anterior,posterior,lateral,medial and central of the right lung were (-712 ± 90),(-575±121),(-657±90),(-619±95),(-670±87) HU respectively.The statistical differences of these five measurement areas were significant at both inspiration and expiration phase (F=12.55,11.29,23.31,25.47,P＜0.01).The posterior lung density was the highest and the anterior was the lowest.As for the other measurement areas,in descending order were medial,lateral,and central.Conclusion The lung density at end inspiration and end expiration in children under 5 years old is described to provide reference for the clinical work.