中华实验眼科杂志
中華實驗眼科雜誌
중화실험안과잡지
CHINESE JOURNAL OF EXPERIMENTAL OPHTHALMOLOGY
2015年
1期
51-54
,共4页
佘海澄%李栋军%杨文利%陈伟%王子杨%魏文斌
佘海澄%李棟軍%楊文利%陳偉%王子楊%魏文斌
사해징%리동군%양문리%진위%왕자양%위문빈
脉络膜%脉络膜肿瘤/诊断%血管瘤/诊断%对比增强超声
脈絡膜%脈絡膜腫瘤/診斷%血管瘤/診斷%對比增彊超聲
맥락막%맥락막종류/진단%혈관류/진단%대비증강초성
Choroid%Choroidal neoplasm/diagnosis%Hemangioma/diagnosis%Contrast-enhanced ultrasound
背景 脉络膜血管瘤是常见的跟部良性肿瘤,典型病例通过临床检查易于诊断,但不典型病例易误诊为眼部恶性肿瘤.超声造影,即对比增强超声(CEUS)是近年来用于占位性病变临床诊断的影像学检查技术,但在眼科的应用较少. 目的 研究脉络膜血管瘤CEUS的表现特点. 方法 对2010年7月至2012年12月在北京同仁医院经临床综合检查诊断为脉络膜血管瘤的58例58眼进行CEUS检查,并分析其CEUS特点.应用时间-强度分析分别对脉络膜血管瘤及正常眼眶组织的显影上升时间(RT)、达峰时间(TTP)、峰值强度(MI)及平均渡越时间(mTT)进行测量和定量比较,并采用配对秩和检验对检查结果的差异进行比较.结果 CEUS检查显示,脉络膜血管瘤患者注射造影剂后随时间的推移,病灶完全显影,并呈高信号影像,显影的消退时间迟于正常眶内组织.脉络膜血管瘤病灶MI、RT、TTP和mTT分别为294.20％(217.35％,373.25％)、21.30(17.35,23.35)s、25.00(21.68,27.48)s和59.30(51.08,78.35)s,其中位数明显大于正常眶内组织的100.00％(100.00％,100.00％)、17.75(15.00,20.30)s、22.40(18.35,24.63)s和47.25(40.90,57.23)s,差异均有统计学意义(Z=-6.608,-4.998,-4.650,-4.332,均P＜0.001).结论 脉络膜血管瘤的CEUS表现具有特异性,有助于脉络膜血管瘤的鉴别诊断.
揹景 脈絡膜血管瘤是常見的跟部良性腫瘤,典型病例通過臨床檢查易于診斷,但不典型病例易誤診為眼部噁性腫瘤.超聲造影,即對比增彊超聲(CEUS)是近年來用于佔位性病變臨床診斷的影像學檢查技術,但在眼科的應用較少. 目的 研究脈絡膜血管瘤CEUS的錶現特點. 方法 對2010年7月至2012年12月在北京同仁醫院經臨床綜閤檢查診斷為脈絡膜血管瘤的58例58眼進行CEUS檢查,併分析其CEUS特點.應用時間-彊度分析分彆對脈絡膜血管瘤及正常眼眶組織的顯影上升時間(RT)、達峰時間(TTP)、峰值彊度(MI)及平均渡越時間(mTT)進行測量和定量比較,併採用配對秩和檢驗對檢查結果的差異進行比較.結果 CEUS檢查顯示,脈絡膜血管瘤患者註射造影劑後隨時間的推移,病竈完全顯影,併呈高信號影像,顯影的消退時間遲于正常眶內組織.脈絡膜血管瘤病竈MI、RT、TTP和mTT分彆為294.20％(217.35％,373.25％)、21.30(17.35,23.35)s、25.00(21.68,27.48)s和59.30(51.08,78.35)s,其中位數明顯大于正常眶內組織的100.00％(100.00％,100.00％)、17.75(15.00,20.30)s、22.40(18.35,24.63)s和47.25(40.90,57.23)s,差異均有統計學意義(Z=-6.608,-4.998,-4.650,-4.332,均P＜0.001).結論 脈絡膜血管瘤的CEUS錶現具有特異性,有助于脈絡膜血管瘤的鑒彆診斷.
배경 맥락막혈관류시상견적근부량성종류,전형병례통과림상검사역우진단,단불전형병례역오진위안부악성종류.초성조영,즉대비증강초성(CEUS)시근년래용우점위성병변림상진단적영상학검사기술,단재안과적응용교소. 목적 연구맥락막혈관류CEUS적표현특점. 방법 대2010년7월지2012년12월재북경동인의원경림상종합검사진단위맥락막혈관류적58례58안진행CEUS검사,병분석기CEUS특점.응용시간-강도분석분별대맥락막혈관류급정상안광조직적현영상승시간(RT)、체봉시간(TTP)、봉치강도(MI)급평균도월시간(mTT)진행측량화정량비교,병채용배대질화검험대검사결과적차이진행비교.결과 CEUS검사현시,맥락막혈관류환자주사조영제후수시간적추이,병조완전현영,병정고신호영상,현영적소퇴시간지우정상광내조직.맥락막혈관류병조MI、RT、TTP화mTT분별위294.20％(217.35％,373.25％)、21.30(17.35,23.35)s、25.00(21.68,27.48)s화59.30(51.08,78.35)s,기중위수명현대우정상광내조직적100.00％(100.00％,100.00％)、17.75(15.00,20.30)s、22.40(18.35,24.63)s화47.25(40.90,57.23)s,차이균유통계학의의(Z=-6.608,-4.998,-4.650,-4.332,균P＜0.001).결론 맥락막혈관류적CEUS표현구유특이성,유조우맥락막혈관류적감별진단.
Background Choroidal hemangioma is a common benign intraocular tumor.Typical choroidal hemangioma is comparably easy to diagnose,but untypical one might be misdiagnosed as malignant tumor.Contrastenhanced ultrasound (CEUS) has been used to diagnose multiple neoplasm for the past few years.However,the application of CEUSin ophthalmology is less.Objective This study was to investigate the CEUS characteristics of choroidal hemangioma.Methods Fifty-eight eyes of 58 patients who were diagnosed as choroidal hemangioma were included in Beijing Tongren Hospital during July 2010 to December 2012.CEUS was performed on the patients to check the manifestations of choroidal hemangioma.A time-intensity analysis was employed to quantitatively analyzed and compared the maximum intensity (MI),rising time (RT),time to peak (TTP),and mean transit time (mTT) between the choroidal hemangioma and normal orbital tissue and the parameters were contrasted using Wilcoxon signed-rank test.Results CEUS showed that choroidal hemangioma was gradually enhanced by the contrast after intravenous injection of sulphur hexafluoride microbubbles with a high-reference signal in choroidal hemangioma,and the fading procedure was slower in choroidal hemangioma than that of normal orbital tissue.MI,RT,TTP,and mTT were294.20％ (217.35％,373.25％),21.30 (17.35,23.35) s,25.00 (21.68,27.48) s and 59.30 (51.08,78.35) s in the choroidal hemangioma,which were significantly higher than 100.00％ (100.00％,100.00％),17.75 (15.00,20.30) s,22.40 (18.35,24.63) s and 47.25 (40.90,57.23) s in the normal orbital tissue (Z =-6.608,-4.998,-4.650,-4.332,all at P＜0.001).Conclusions Choroidal hemangioma has its own CEUS manifestation characteristics.CEUS is helpful to the differential diagnosis of choroidal hemangioma.
