国际外科学杂志
國際外科學雜誌
국제외과학잡지
INTERNATIONAL JOURNAL OF SURGERY
2014年
12期
845-849
,共5页
镇痛%免疫%肿瘤%围术期
鎮痛%免疫%腫瘤%圍術期
진통%면역%종류%위술기
Analgesia%Immunity%Neoplasms%Perioperative period
恶性肿瘤患者围术期存在免疫功能抑制,且术后疼痛可抑制机体免疫功能.有效的术后镇痛能缓解围术期机体免疫功能抑制,并减少肿瘤复发转移.然而,不同镇痛药物及镇痛方式对机体免疫功能的影响不尽相同.本文就不同镇痛药物及镇痛方式对恶性肿瘤患者围术期免疫功能影响的研究进展作一综述,以期为肿瘤患者提供更合适的术后镇痛方案,有利于术后免疫平衡调节,减少肿瘤复发风险并改善预后.
噁性腫瘤患者圍術期存在免疫功能抑製,且術後疼痛可抑製機體免疫功能.有效的術後鎮痛能緩解圍術期機體免疫功能抑製,併減少腫瘤複髮轉移.然而,不同鎮痛藥物及鎮痛方式對機體免疫功能的影響不儘相同.本文就不同鎮痛藥物及鎮痛方式對噁性腫瘤患者圍術期免疫功能影響的研究進展作一綜述,以期為腫瘤患者提供更閤適的術後鎮痛方案,有利于術後免疫平衡調節,減少腫瘤複髮風險併改善預後.
악성종류환자위술기존재면역공능억제,차술후동통가억제궤체면역공능.유효적술후진통능완해위술기궤체면역공능억제,병감소종류복발전이.연이,불동진통약물급진통방식대궤체면역공능적영향불진상동.본문취불동진통약물급진통방식대악성종류환자위술기면역공능영향적연구진전작일종술,이기위종류환자제공경합괄적술후진통방안,유리우술후면역평형조절,감소종류복발풍험병개선예후.
Perioperative immunosuppression exists in cancer patients are as a result of their own disease,and postoperative pain inhibit immunological function.The effective postoperative analgesia can relieve the suppression of cell-mediated immunity,as well as reducing tumor recurrence and metastasis.However,diverse range of analgesic agents and techniques have a different impact on immune function.This article reviews the influence of various analgesic agents and techniques on the perioperative immune function of cancer patients so as to provide more suitable analgesia techniques,which is beneficial for regulating of immune balance,lessening tumor recurrence and improving prognosis.
