CAJ | 학술논문

目的：建立展神经损伤电针刺激的动物模型，研究电针刺激对展神经损伤修复的疗效。方法24只Bea?gle犬随机均分为单纯损伤组(对照组)及损伤后电针刺激组(实验组)。行展神经脑池段压榨损伤，展神经刺激电极及外直肌记录电极植入。于术后1～12周，测量2组瞳孔中心至外眦内侧缘距离。结果所有Beagle犬均能耐受手术，颅内刺激电极和外直肌记录电极成功植入；术后1～2周，2组Beagle犬瞳孔中心至外眦内侧缘距离比较差异无统计学意义，术后4～12周，实验组Beagle犬瞳孔中心至外眦内侧缘距离小于对照组(P＜0.01)。结论成功建立应用于展神经损伤电针刺激的动物模型，电针刺激可以明显促进损伤的展神经恢复。
목적：건립전신경손상전침자격적동물모형，연구전침자격대전신경손상수복적료효。방법24지Bea?gle견수궤균분위단순손상조(대조조)급손상후전침자격조(실험조)。행전신경뇌지단압자손상，전신경자격전겁급외직기기록전겁식입。우술후1～12주，측량2조동공중심지외자내측연거리。결과소유Beagle견균능내수수술，로내자격전겁화외직기기록전겁성공식입；술후1～2주，2조Beagle견동공중심지외자내측연거리비교차이무통계학의의，술후4～12주，실험조Beagle견동공중심지외자내측연거리소우대조조(P＜0.01)。결론성공건립응용우전신경손상전침자격적동물모형，전침자격가이명현촉진손상적전신경회복。
Objective To establish Beagle dogs’model of abducens nerves injury and to observe the clinical therapeu?tic effect of electroacupuncture treatment. Methods Twenty-four Beagle dogs were randomly divided into simple crush group (control group) and crush with electrical stimulation group (experimental group). Cisternal segment of the abducens nerve was given a crush injury, then electrodes were implanted to stimulate the abducens nerve and lateral rectus muscle. Distance between the center of the pupil to medial margin of extraocular adjoin was measured from 1 to 12 weeks after opera?tions. Results All procedures used in the study were well tolerated by Beagle dogs. Electrode implantation to stimulate the lateral rectus muscle and the abducens nerve behind of cavemous sinus was successful. There was no statistical significance of the distance between the two groups from 1 to 2 weeks after operations, and the distance was shorter in experimental group than that in control group from 4 to 12 weeks after operations (P<0.01). Conclusion The animal models established to study electroacupuncture treatment of the injured abducens nerves was successful. Electroacupuncture can promote the re?covery of the injured abducens nerves obviously.