CAJ | 학술논문

脊索瘤是一种较为罕见的起源于胚胎时期残余脊索组织的恶性原发性骨肿瘤，呈低至中度恶性。脊索瘤以局部侵袭性及高复发性为特点，治疗上以手术为主，其对传统的放化疗均不敏感且患者术后复发率较高，预后较差。文中对脊索瘤治疗的基础与临床研究进展作一综述。
척색류시일충교위한견적기원우배태시기잔여척색조직적악성원발성골종류，정저지중도악성。척색류이국부침습성급고복발성위특점，치료상이수술위주，기대전통적방화료균불민감차환자술후복발솔교고，예후교차。문중대척색류치료적기출여림상연구진전작일종술。
Chordoma is a rare low and moderate-grade malignant tumor originated in the embryonic period residual notochord tissue.Due to its critical location, local aggressive nature, and high recurrence, chordoma is not sensitive to radiotherapy and chemo-therapy with poor prognosis .Surgery is the main treatment method .Here we present a review focusing on basic and clinical research progress of chordoma .