医学影像学杂志
醫學影像學雜誌
의학영상학잡지
JOURNAL OF MEDICAL IMAGING
2015年
2期
194-196
,共3页
婴幼儿%结节性硬化症%磁共振成像
嬰幼兒%結節性硬化癥%磁共振成像
영유인%결절성경화증%자공진성상
Infant%Tuberous sclerosis%Magnetic resonance imaging
目的：探讨婴幼儿结节性硬化症（tuberous sclerosis ，TS）的MRI表现，进行早期诊断。方法回顾性分析12例经临床及基因分析检查证实的婴幼儿 TS 病例，分析其颅脑 MRI 的特征性改变。结果12例患者均发现室管膜下结节，共84个；皮层下结节 5 例，共28个；10例发现白质异常信号，共31个。结论 MRI 对 TS 的中枢神经系统改变敏感，尤其是婴幼儿在没有形成钙化前，MRI 具有与成人不同的独特信号和形态分布，尤其是 T1 WI 序列对病灶的显示尤为敏感，以提高早期诊断的准确率。
目的：探討嬰幼兒結節性硬化癥（tuberous sclerosis ，TS）的MRI錶現，進行早期診斷。方法迴顧性分析12例經臨床及基因分析檢查證實的嬰幼兒 TS 病例，分析其顱腦 MRI 的特徵性改變。結果12例患者均髮現室管膜下結節，共84箇；皮層下結節 5 例，共28箇；10例髮現白質異常信號，共31箇。結論 MRI 對 TS 的中樞神經繫統改變敏感，尤其是嬰幼兒在沒有形成鈣化前，MRI 具有與成人不同的獨特信號和形態分佈，尤其是 T1 WI 序列對病竈的顯示尤為敏感，以提高早期診斷的準確率。
목적：탐토영유인결절성경화증（tuberous sclerosis ，TS）적MRI표현，진행조기진단。방법회고성분석12례경림상급기인분석검사증실적영유인 TS 병례，분석기로뇌 MRI 적특정성개변。결과12례환자균발현실관막하결절，공84개；피층하결절 5 례，공28개；10례발현백질이상신호，공31개。결론 MRI 대 TS 적중추신경계통개변민감，우기시영유인재몰유형성개화전，MRI 구유여성인불동적독특신호화형태분포，우기시 T1 WI 서렬대병조적현시우위민감，이제고조기진단적준학솔。
Objective To study the MRI manifestations of tuberous sclerosis (TS) in infants so as to make an early diag‐nosis for this disorder .Methods We retrospectively analyzed of 12 patients with TS confirmed by clinic and genetic test and analyzed the characteristic changes in cerebral MRI .Results A total of 84 nodules in these 12 cases were found .In this work ,5 cases were located in subcortex ,with a total of 28 nodules ,and 10 cases were found abnormal signals in white matter ,with a total of 31 nodules .Conclusion MRI is sensitive to the change in central nervous system ,especially for infants and young children before no calcification formation .MRI has a unique signal and form distribution ,which is different from these of adults ,especially that T 1 WI sequence is particularly sensitive for showing lesions ,thereby impro‐ving the accuracy of early diagnosis .
