中国药师
中國藥師
중국약사
CHINA PHARMACIST
2015年
2期
275-276
,共2页
右美托咪定%小儿%眼科手术%恢复质量
右美託咪定%小兒%眼科手術%恢複質量
우미탁미정%소인%안과수술%회복질량
Dexmedetomidine%Children%Ophthalmic surgery%Recovery quality
目的：：观察小儿眼科手术应用右美托咪定麻醉对患儿恢复质量的影响。方法：126例小儿眼科手术患儿随机分组为对照组和观察组。2组采用相同诱导方案,对照组术中靶控丙泊酚；观察组诱导前给予右美托咪定0.6μg·kg-1 iv,10 min内输注完,术中靶控丙泊酚维持,术前10 min停止麻醉药物输注。观察比较2组患儿麻醉苏醒期间发生咳嗽的次数、程度,发生躁动情况,拔管时间等。结果：观察组咳嗽和躁动发生率分别为36.51%、4.76%,明显低于对照组的74.60%、33.33%( P<0.05)。2组患儿咳喘程度比较,差异有统计学意义(P<0.05)；而两组患儿首次咳嗽时间和拔管时间比较,差异无统计学意义(P>0.05)。结论：右美托咪定麻醉应用于小儿手术中可有效控制患儿麻醉复苏期咳嗽次数和咳嗽程度,减少躁动发生,提高临床麻醉复苏质量。
目的：：觀察小兒眼科手術應用右美託咪定痳醉對患兒恢複質量的影響。方法：126例小兒眼科手術患兒隨機分組為對照組和觀察組。2組採用相同誘導方案,對照組術中靶控丙泊酚；觀察組誘導前給予右美託咪定0.6μg·kg-1 iv,10 min內輸註完,術中靶控丙泊酚維持,術前10 min停止痳醉藥物輸註。觀察比較2組患兒痳醉囌醒期間髮生咳嗽的次數、程度,髮生躁動情況,拔管時間等。結果：觀察組咳嗽和躁動髮生率分彆為36.51%、4.76%,明顯低于對照組的74.60%、33.33%( P<0.05)。2組患兒咳喘程度比較,差異有統計學意義(P<0.05)；而兩組患兒首次咳嗽時間和拔管時間比較,差異無統計學意義(P>0.05)。結論：右美託咪定痳醉應用于小兒手術中可有效控製患兒痳醉複囌期咳嗽次數和咳嗽程度,減少躁動髮生,提高臨床痳醉複囌質量。
목적：：관찰소인안과수술응용우미탁미정마취대환인회복질량적영향。방법：126례소인안과수술환인수궤분조위대조조화관찰조。2조채용상동유도방안,대조조술중파공병박분；관찰조유도전급여우미탁미정0.6μg·kg-1 iv,10 min내수주완,술중파공병박분유지,술전10 min정지마취약물수주。관찰비교2조환인마취소성기간발생해수적차수、정도,발생조동정황,발관시간등。결과：관찰조해수화조동발생솔분별위36.51%、4.76%,명현저우대조조적74.60%、33.33%( P<0.05)。2조환인해천정도비교,차이유통계학의의(P<0.05)；이량조환인수차해수시간화발관시간비교,차이무통계학의의(P>0.05)。결론：우미탁미정마취응용우소인수술중가유효공제환인마취복소기해수차수화해수정도,감소조동발생,제고림상마취복소질량。
Objective:To observe the effect of dexmedetomidine used in ophthalmic surgery anesthesia on the recovery quality in children. Methods:Totally 126 children with ophthalmic surgery were randomly divided into the control group and the observation group with the same induction program. The control group was given propofol with target controlled infusion during the operation, while the observation group was given dexmedetomidine 0. 6μg·kg-1 before the induction, and infused up in 10min, propofol with target controlled infusion was used during the operation, and stopped infusion 10min before the end of the operation. The cough number and degree, the occurrence of agitation and extubation time of the two groups were observed and compared during the anesthesia recovery period. Results:The cough incidence and agitation incidence was 36. 51% and 4. 76% in the observation group, respectively, which were significantly lower than those in the control group (74. 60% and 33. 33%, P<0. 05). The cough degree between the two groups showed significant difference (P<0. 05). The first cough time and the extubation time between the two groups showed no significant difference (P>0. 05). Conclusion:Dexmedetomidine used in ophthalmic surgery anesthesia of children can effectively control cough frequency and degree during the recovery period and reduce the agitation to improve the quality of clinical anesthesia recovery.
