CAJ | 학술논문

目的：：了解不同临床标本分离出大肠埃希菌的耐药特点及差异，为临床控制医院感染及合理用药提供依据。方法：回顾性分析2013年我院使用BD Phoenix 100全自动细菌鉴定药敏仪及药敏试验卡从临床送检样本中分离鉴定出的大肠埃希菌对常见抗菌药的耐药性，并比较不同标本所检出大肠埃希菌的耐药性差异。结果：2013年从临床各科送检样本中共分离出大肠埃希菌936株，大肠埃希菌对常用抗菌药呈高水平耐药。不同标本分离的大肠埃希菌对抗菌药的耐药率存在差异，痰液分离出的大肠埃希菌耐药性明显高于其他标本。结论：临床分离的大肠埃希菌耐药现状十分严重且不同标本间耐药性存在差异，应按照药敏结果合理使用抗菌药。
목적：：료해불동림상표본분리출대장애희균적내약특점급차이，위림상공제의원감염급합리용약제공의거。방법：회고성분석2013년아원사용BD Phoenix 100전자동세균감정약민의급약민시험잡종림상송검양본중분리감정출적대장애희균대상견항균약적내약성，병비교불동표본소검출대장애희균적내약성차이。결과：2013년종림상각과송검양본중공분리출대장애희균936주，대장애희균대상용항균약정고수평내약。불동표본분리적대장애희균대항균약적내약솔존재차이，담액분리출적대장애희균내약성명현고우기타표본。결론：림상분리적대장애희균내약현상십분엄중차불동표본간내약성존재차이，응안조약민결과합리사용항균약。
Objective:To investigate the antimicrobial resistance spectrum of Escherichia coli isolated from different clinical sam-ples to guide the nosocomial infection control and rational use of antibiotics. Methods:Escherichia coli from clinical samples were isola-ted and tested by microbiological assay system of BD Phoenix 100 and susceptibility test card in 2013. The drug resistance was analyzed and compared retrospectively. Results: There were 936 strains of Escherichia coli isolated from our hospital in 2013. Escherichia coli was resistant to common antibiotics at high level. Escherichia coli strains isolated from different samples varied in the drug susceptibili-ty. The resistance rate of the strains from sputum samples was higher than that from the other samples. Conclusion:The status of drug resistance of clinical isolated Escherichia coli to antibiotics is very serious. Escherichia coli isolated from different samples show different drug resistant features, and the antimicrobial therapy should be considered according to the antimicrobial susceptibility tests.