中国药师
中國藥師
중국약사
CHINA PHARMACIST
2015年
2期
262-263,264
,共3页
罗哌卡因%舒芬太尼%硬膜外阻滞镇痛%分娩
囉哌卡因%舒芬太尼%硬膜外阻滯鎮痛%分娩
라고잡인%서분태니%경막외조체진통%분면
Ropivacaine%Fentanyi%Epidural block analgesia%Childbirth
目的：：探讨硬膜外阻滞镇痛的分娩效果及对母婴的影响。方法：采用回顾性研究方法。200例初产妇根据分娩镇痛情况分为两组,观察组100例宫口开大2~3 cm时于第2~3腰椎硬膜外穿刺并置管,首次注入0.075%盐酸罗哌卡因+舒芬太尼10 ml,之后予0.075%盐酸罗哌卡因+舒芬太尼自控镇痛泵持续给药6~8 ml·h-1,宫口近开全停止给药。对照组100例宫口开大2~3 cm时不使用任何麻醉药物。观察比较两组产妇镇痛效果,产程时间及分娩方式、产后出血量、胎儿窘迫、产后出血情况。结果：观察组镇痛有效率97.0%,明显高于对照组的10.0%(P<0.05)；观察组第一产程时间明显短于对照组(P<0.05),阴道助产率明显低于对照组(P<0.05)。两组新生儿窒息发生率和1 min Apgar评分,以及患者产后24 h出血量及出血率等比较,差异均无统计学意义(P>0.05)。结论：低浓度罗哌卡因联合舒芬太尼硬膜外阻滞用于分娩镇痛,有较好镇痛效果,可缩短产程时间,促进分娩顺利进行。
目的：：探討硬膜外阻滯鎮痛的分娩效果及對母嬰的影響。方法：採用迴顧性研究方法。200例初產婦根據分娩鎮痛情況分為兩組,觀察組100例宮口開大2~3 cm時于第2~3腰椎硬膜外穿刺併置管,首次註入0.075%鹽痠囉哌卡因+舒芬太尼10 ml,之後予0.075%鹽痠囉哌卡因+舒芬太尼自控鎮痛泵持續給藥6~8 ml·h-1,宮口近開全停止給藥。對照組100例宮口開大2~3 cm時不使用任何痳醉藥物。觀察比較兩組產婦鎮痛效果,產程時間及分娩方式、產後齣血量、胎兒窘迫、產後齣血情況。結果：觀察組鎮痛有效率97.0%,明顯高于對照組的10.0%(P<0.05)；觀察組第一產程時間明顯短于對照組(P<0.05),陰道助產率明顯低于對照組(P<0.05)。兩組新生兒窒息髮生率和1 min Apgar評分,以及患者產後24 h齣血量及齣血率等比較,差異均無統計學意義(P>0.05)。結論：低濃度囉哌卡因聯閤舒芬太尼硬膜外阻滯用于分娩鎮痛,有較好鎮痛效果,可縮短產程時間,促進分娩順利進行。
목적：：탐토경막외조체진통적분면효과급대모영적영향。방법：채용회고성연구방법。200례초산부근거분면진통정황분위량조,관찰조100례궁구개대2~3 cm시우제2~3요추경막외천자병치관,수차주입0.075%염산라고잡인+서분태니10 ml,지후여0.075%염산라고잡인+서분태니자공진통빙지속급약6~8 ml·h-1,궁구근개전정지급약。대조조100례궁구개대2~3 cm시불사용임하마취약물。관찰비교량조산부진통효과,산정시간급분면방식、산후출혈량、태인군박、산후출혈정황。결과：관찰조진통유효솔97.0%,명현고우대조조적10.0%(P<0.05)；관찰조제일산정시간명현단우대조조(P<0.05),음도조산솔명현저우대조조(P<0.05)。량조신생인질식발생솔화1 min Apgar평분,이급환자산후24 h출혈량급출혈솔등비교,차이균무통계학의의(P>0.05)。결론：저농도라고잡인연합서분태니경막외조체용우분면진통,유교호진통효과,가축단산정시간,촉진분면순리진행。
Objective: To investigate the effect of epidural block analgesia on childbirth, mother and child. Methods: A retro-spective study was used. Totally 200 primipara were divided into two groups according to the analgesia method. The 100 cases in the observation group was undergone lumbar epidural puncture and cathetering at the 2-3 section when the cervix was with 2-3cm opening, 0. 075% ropivacaine hydrochloride and sufentanil 10ml was infused firstly, and then 0. 075% ropivacaine and sufentanil was infused continuously through a self-control analgesia pump at the speed of 6-8ml·h-1 till the cervix was nearly all opened. The other 100 cases in the control group were without anesthesia when the cervix was with 2-3cm opening. The analgesia effect, labor time, delivery mode, postpartum hemorrhage amount, fetal distress and postpartum hemorrhage of the two groups were compared. Results:The analgesic ef-fective rate of the observation group was 97. 0%, which was significantly higher than that of the control group (10. 0%, P<0. 05). The first stage of birth process in the observation group was significantly shorter than that in the control group (P<0. 05), and the va-ginal delivery rate was significantly lower than that in the control group (P<0. 05). The incidence of neonatal asphyxia, 1min Apgar score, 24-hour postpartum hemorrhage amount and bleeding rate showed no statistically significant difference between the two groups (P>0. 05). Conclusion:Ropivacaine at low concentration combined with sufentanil used in epidural block analgesia has promising analgesic effect, which can shorten labor time to promote the smooth delivery.
