中国药师
中國藥師
중국약사
CHINA PHARMACIST
2015年
2期
258-259,260
,共3页
抗菌药%妇产科%Ⅱ类切口手术%预防%干预
抗菌藥%婦產科%Ⅱ類切口手術%預防%榦預
항균약%부산과%Ⅱ류절구수술%예방%간예
Antibiotics%Obstetrics and gynecology%Type Ⅱ incision operation%Prophylaxis%Intervention
目的：：探讨干预前后我院妇产科Ⅱ类切口手术围手术期预防应用抗菌药的合理性，评价干预措施成效。方法：分别收集2012年4月~2013年3月(干预前)及2013年4月~2014年3月(干预后)我院妇产科Ⅱ类切口手术围手术期预防应用抗菌药患者的病历，对照组(干预前)共274份病历，干预组(干预后)321份，比较干预前后围手术期预防应用抗菌药合理性。结果：与对照组比较，干预组平均用药时间、平均住院时间、平均抗菌药费用均明显降低(P<0.05)，两组的药品不良反应及手术切口感染率差异均无统计学意义(P>0.05)。与对照组比较，干预组“抗菌药选择不合理、无指征联合使用、用药时机不合理、术后用药时间过长、抗菌药用法用量不当和溶媒选择不当”发生率均明显降低(P<0.05)。结论：在实施管理干预措施后，我院妇产科围手术期预防应用抗菌药合理性明显提高。
目的：：探討榦預前後我院婦產科Ⅱ類切口手術圍手術期預防應用抗菌藥的閤理性，評價榦預措施成效。方法：分彆收集2012年4月~2013年3月(榦預前)及2013年4月~2014年3月(榦預後)我院婦產科Ⅱ類切口手術圍手術期預防應用抗菌藥患者的病歷，對照組(榦預前)共274份病歷，榦預組(榦預後)321份，比較榦預前後圍手術期預防應用抗菌藥閤理性。結果：與對照組比較，榦預組平均用藥時間、平均住院時間、平均抗菌藥費用均明顯降低(P<0.05)，兩組的藥品不良反應及手術切口感染率差異均無統計學意義(P>0.05)。與對照組比較，榦預組“抗菌藥選擇不閤理、無指徵聯閤使用、用藥時機不閤理、術後用藥時間過長、抗菌藥用法用量不噹和溶媒選擇不噹”髮生率均明顯降低(P<0.05)。結論：在實施管理榦預措施後，我院婦產科圍手術期預防應用抗菌藥閤理性明顯提高。
목적：：탐토간예전후아원부산과Ⅱ류절구수술위수술기예방응용항균약적합이성，평개간예조시성효。방법：분별수집2012년4월~2013년3월(간예전)급2013년4월~2014년3월(간예후)아원부산과Ⅱ류절구수술위수술기예방응용항균약환자적병력，대조조(간예전)공274빈병력，간예조(간예후)321빈，비교간예전후위수술기예방응용항균약합이성。결과：여대조조비교，간예조평균용약시간、평균주원시간、평균항균약비용균명현강저(P<0.05)，량조적약품불량반응급수술절구감염솔차이균무통계학의의(P>0.05)。여대조조비교，간예조“항균약선택불합리、무지정연합사용、용약시궤불합리、술후용약시간과장、항균약용법용량불당화용매선택불당”발생솔균명현강저(P<0.05)。결론：재실시관리간예조시후，아원부산과위수술기예방응용항균약합이성명현제고。
Objective:To investigate the rationality of prophylactic antibiotics application during perioperative period in the pa-tients with type Ⅱ incision operation in gynecology and obstetrics in our hospital after the intervention. Methods:Totally 274 medical records of obstetrics and gynecology patients with typeⅡincision operation in our hospital from April 2012 to March 2013 were collect-ed as the control group, another 321 medical records of obstetrics and gynecology patients with typeⅡincision operation in our hospital from April 2013 to March 2014 were collected as the intervention group. The rationality of prophylactic antibiotics application before and after the intervention was compared. Results:Compared with those in the control group, the average administration time, the hos-pitalization time and the cost of antimicrobial agents were significantly decreased in the intervention group (P<0. 05). The incidence of adverse drug reactions and operation incision infection between the two groups was not significant difference (P>0. 05). Compared with those in the control group, the incidence of irrational choice of antibacterial drugs, the combined use without indication, irrational medication time,over-time use, inappropriate use and improper choice of solvents in the intervention group was significantly reduced ( P<0. 05). Conclusion:After the intervention, the rationality of prophylactic antibiotics application during perioperative period in the patients with type Ⅱ incision operation in gynecology and obstetrics in our hospital is improved significantly.
