中国药物警戒
中國藥物警戒
중국약물경계
CHINESE JOURNAL OF PHARMACOVIGILANCE
2015年
2期
99-101
,共3页
山豆根%不良反应%合理用药
山豆根%不良反應%閤理用藥
산두근%불량반응%합리용약
Sophora Tonkinensis Gagnep.%adverse drug reaction%rational drug use
目的:探讨山豆根及其制剂引起不良反应发生的一般规律,为临床合理用药提供参考。方法通过检索现代医学期刊数据库和中国中医药数据库,对收集到的111例山豆根及其相关制剂致不良反应的文献报道进行统计分析。结果口服山豆根日剂量超过5 g或肌内注射肝炎灵注射液4 mL即出现不良反应,其不良反应以消化系统和神经系统的损害为主,分别占山豆根引起不良反应的32.21%和31.46%。结论山豆根作为临床治疗咽喉肿痛的常用药物,临床医师/药师应严格控制用药剂量,加强合理用药,避免或减少其不良反应的发生。
目的:探討山豆根及其製劑引起不良反應髮生的一般規律,為臨床閤理用藥提供參攷。方法通過檢索現代醫學期刊數據庫和中國中醫藥數據庫,對收集到的111例山豆根及其相關製劑緻不良反應的文獻報道進行統計分析。結果口服山豆根日劑量超過5 g或肌內註射肝炎靈註射液4 mL即齣現不良反應,其不良反應以消化繫統和神經繫統的損害為主,分彆佔山豆根引起不良反應的32.21%和31.46%。結論山豆根作為臨床治療嚥喉腫痛的常用藥物,臨床醫師/藥師應嚴格控製用藥劑量,加彊閤理用藥,避免或減少其不良反應的髮生。
목적:탐토산두근급기제제인기불량반응발생적일반규률,위림상합리용약제공삼고。방법통과검색현대의학기간수거고화중국중의약수거고,대수집도적111례산두근급기상관제제치불량반응적문헌보도진행통계분석。결과구복산두근일제량초과5 g혹기내주사간염령주사액4 mL즉출현불량반응,기불량반응이소화계통화신경계통적손해위주,분별점산두근인기불량반응적32.21%화31.46%。결론산두근작위림상치료인후종통적상용약물,림상의사/약사응엄격공제용약제량,가강합리용약,피면혹감소기불량반응적발생。
Objective To investigate relevant factors of the adverse drug reaction(ADR) induced by Sophora Tonkinensis and related preparations, and provide the scientific reference for the safe and rational use in clinic. Methods With retrospective case study, 111 cases of ADR induced by Sophora Tonkinensis and related preparations were analyzed, which were collected from medical journal database and traditional Chinese medicine database. Results Adverse reaction will occur when orally taken daily dose more than 5 g or intramuscularly injected 4 mL. The damage to digestive and nervous system was the most common, which accounted for 32.21%and 31.46%of total adverse reactions respectively. Conclusion Sophora Tonkinensis as a common traditional Chinese medicine is used for clinical treatment of sore throat and physicians/pharmacists should control the dosage strictly to avoid or reduce the incidence of ADR.