CAJ | 학술논문

目的：观察丹参酮IIA磺酸钠联合氯吡格雷对心绞痛的疗效和不良反应。方法：118例不稳定型心绞痛患者随机分成两组，两组均给予常规治疗，对照组给予硝酸酯类、β受体阻断剂或钙拮抗剂、低分子量肝素、血管紧张素转换酶抑制剂等，观察组加用丹参酮IIA磺酸钠和氯吡格雷，疗程2周，观察临床疗效和不良反应。结果：观察组总有效率91.5%，明显优于对照组（69.5%），两组比较差异有统计学意义（P<0.05），观察组心电图治疗总有效率93.2%，明显高于对照组（71.2%），两组比较差异有统计学意义（P<0.05）。无明显的不良反应。结论：丹参酮IIA磺酸钠联合硫酸氢氯吡格雷治疗不稳定型心绞痛疗效明显，安全，值得推广。
목적：관찰단삼동IIA광산납연합록필격뢰대심교통적료효화불량반응。방법：118례불은정형심교통환자수궤분성량조，량조균급여상규치료，대조조급여초산지류、β수체조단제혹개길항제、저분자량간소、혈관긴장소전환매억제제등，관찰조가용단삼동IIA광산납화록필격뢰，료정2주，관찰림상료효화불량반응。결과：관찰조총유효솔91.5%，명현우우대조조（69.5%），량조비교차이유통계학의의（P<0.05），관찰조심전도치료총유효솔93.2%，명현고우대조조（71.2%），량조비교차이유통계학의의（P<0.05）。무명현적불량반응。결론：단삼동IIA광산납연합류산경록필격뢰치료불은정형심교통료효명현，안전，치득추엄。
Objective: To observe clinical effects and side effects of Tanshinone IIA sulfonate plus Clopidogrel on UAP. Methods: 118 patients with UAP were randomly divided into two groups. The control group was given nitrates,β-blockers or calcium antagonists, low molecular weight heparin, angiotensin converting enzyme inhibitors and so on; while the observation group was given Tanshinone IIA sulfonate plus Clopidogrel more, with 2 courses of treatment, clincial effects and side effects were observed. Results: The total efficiency in the observation group (91.5%) was significantly better than that (69.5%) in the control group (P<0.05). The total efficiency of ECG in the observation group (93.2%) was significantly better than that (71.2%) in the control group (P<0.05), without significant adverse reactions. Conclusion: Clinical efficacy of Tanshinone IIA sulfonate plus Clopidogrel on UAP was confirmed, safe, and worthy of clinical promotion.