北京大学学报（医学版）
北京大學學報（醫學版）
북경대학학보（의학판）
JOURNAL OF BEIJING MEDICAL UNIVERSITY(HEALTH SCIENCES)
2015年
1期
19-26
,共8页
詹雅琳%胡文杰%甄敏%徐涛%路瑞芳
詹雅琳%鬍文傑%甄敏%徐濤%路瑞芳
첨아림%호문걸%견민%서도%로서방
拔牙%间隙保持%牙槽骨质丢失%生物相容性材料%磨牙
拔牙%間隙保持%牙槽骨質丟失%生物相容性材料%磨牙
발아%간극보지%아조골질주실%생물상용성재료%마아
Tooth extraction%Space maintenance%Alveolar bone loss%Biocompatible materials%Molar
目的：与自然愈合比较，观察存在骨缺损的磨牙拔牙同期植入去蛋白牛骨基质（ Bio-Oss?）并覆盖可吸收胶原膜（ Bio-Gide?）愈合6个月后牙槽骨高度和宽度的变化。方法：16名患者共18颗因牙周病变拔除的磨牙纳入本研究，分为对照组（牙齿拔除后自然愈合组）和试验组（应用去蛋白牛骨基质与可吸收胶原膜拔牙位点保存组）。术后即刻及术后6个月拍摄平行投照根尖片和锥束计算机体层摄影术（ cone-beam computed tomography ， CBCT ）检查，通过根尖片和CBCT测量评价术后6个月牙槽骨高度和宽度的变化。结果：术后6个月试验组中央和远中颊侧的牙槽骨高度分别增加2．90 mm 和1．45 mm，而对照组中央和远中颊侧的牙槽骨高度分别降低1．00 mm和1．45 mm，两组间差异有统计学意义（P＜0．05），但两组骨宽度变化的差异无统计学意义（P＞0．05）。结论：存在骨缺损的磨牙应用去蛋白牛骨基质与可吸收胶原膜进行拔牙位点保存，可明显增加颊侧牙槽骨高度和牙槽嵴顶根方1 mm和4 mm处牙槽骨宽度。
目的：與自然愈閤比較，觀察存在骨缺損的磨牙拔牙同期植入去蛋白牛骨基質（ Bio-Oss?）併覆蓋可吸收膠原膜（ Bio-Gide?）愈閤6箇月後牙槽骨高度和寬度的變化。方法：16名患者共18顆因牙週病變拔除的磨牙納入本研究，分為對照組（牙齒拔除後自然愈閤組）和試驗組（應用去蛋白牛骨基質與可吸收膠原膜拔牙位點保存組）。術後即刻及術後6箇月拍攝平行投照根尖片和錐束計算機體層攝影術（ cone-beam computed tomography ， CBCT ）檢查，通過根尖片和CBCT測量評價術後6箇月牙槽骨高度和寬度的變化。結果：術後6箇月試驗組中央和遠中頰側的牙槽骨高度分彆增加2．90 mm 和1．45 mm，而對照組中央和遠中頰側的牙槽骨高度分彆降低1．00 mm和1．45 mm，兩組間差異有統計學意義（P＜0．05），但兩組骨寬度變化的差異無統計學意義（P＞0．05）。結論：存在骨缺損的磨牙應用去蛋白牛骨基質與可吸收膠原膜進行拔牙位點保存，可明顯增加頰側牙槽骨高度和牙槽嵴頂根方1 mm和4 mm處牙槽骨寬度。
목적：여자연유합비교，관찰존재골결손적마아발아동기식입거단백우골기질（ Bio-Oss?）병복개가흡수효원막（ Bio-Gide?）유합6개월후아조골고도화관도적변화。방법：16명환자공18과인아주병변발제적마아납입본연구，분위대조조（아치발제후자연유합조）화시험조（응용거단백우골기질여가흡수효원막발아위점보존조）。술후즉각급술후6개월박섭평행투조근첨편화추속계산궤체층섭영술（ cone-beam computed tomography ， CBCT ）검사，통과근첨편화CBCT측량평개술후6개월아조골고도화관도적변화。결과：술후6개월시험조중앙화원중협측적아조골고도분별증가2．90 mm 화1．45 mm，이대조조중앙화원중협측적아조골고도분별강저1．00 mm화1．45 mm，량조간차이유통계학의의（P＜0．05），단량조골관도변화적차이무통계학의의（P＞0．05）。결론：존재골결손적마아응용거단백우골기질여가흡수효원막진행발아위점보존，가명현증가협측아조골고도화아조척정근방1 mm화4 mm처아조골관도。
Objective:To compare the bone dimensional changes following tooth extraction alone with extraction plus ridge preservation ( using deproteinized boving bone mineral Bio-Oss? and bioresorbable collagen mambrane Bio-Gide?) in periodontal compromised extraction sockets .Methods: Eighteen molars of sixteen subjects requiring tooth extraction because of periodontal destruction were enrolled in this study .The subjects were assigned to the control group ( extraction alone , EXT) or to the test group ( ridge-preservation procedure with Bio-Oss? and Bio-Gide?, RP) .Parallel periapical X-rays and cone-beam computed tomography ( CBCT ) scans were taken immediately after tooth extraction alone or plus ridge-preservation ( baseline ) and 6 months later .The changes of horizontal ridge width and vertical ridge height were assessed .Results:At the central buccal aspect , the ridge height increased 2 .9 mm in RP group, and reduced 1.0 mm in EXT group.At the distal buccal aspect , the ridge height increased 1.45 mm in RP group, and reduced 1.45 mm in EXT group.The differences between the groups reached statistical significance (P<0.05).The mean ridge width increased at the 1 mm below the crest (the horizontal ridge width was measured with grafting material at three levels at 1 mm below the most coronal aspect of the crest,HW1), which amounted to 3.40 to 5.80 mm in RP group, and 1.45 to 2.90 mm in EXT group.The mean ridge increased at the 4 mm below the crest ( the horizontal ridge width was measured with grafting material at three levels at 4 mm below the most coronal aspect of the crest ,HW4 ) , which amounted to 0.40 to 3.50 mm in RP group, and reduced 0.10 to increased 0.15 mm in EXT group.The test group and the control group were not significantly different (P>0.05).Conclusion:The ridge-preservation approach using Bio-Oss? in combination with Bio-Gide? can significantly increase vertical ridge height and horizontal ridge width after tooth extraction compared with extraction alone in periodontal compromised molars .
