临床儿科杂志
臨床兒科雜誌
림상인과잡지
2015年
1期
87-91
,共5页
李红红(综述)%沈捷(审校)
李紅紅(綜述)%瀋捷(審校)
리홍홍(종술)%침첩(심교)
艾森曼格综合征%靶向药物%肺动脉高压%先天性心脏病
艾森曼格綜閤徵%靶嚮藥物%肺動脈高壓%先天性心髒病
애삼만격종합정%파향약물%폐동맥고압%선천성심장병
Eisenmenger syndrome%targeting drug%pulmonary arterial hypertension%congenital heart defect
艾森曼格综合征曾被认为是心脏外科矫治手术的禁忌证，需要进行肺移植或心肺联合移植治疗，但由于供体缺乏，大多数患儿只能通过保守治疗延长生存时间。近年来一些临床研究提示肺动脉高压靶向药物治疗ES有一定效果。现就ES治疗的最新进展作一综述。
艾森曼格綜閤徵曾被認為是心髒外科矯治手術的禁忌證，需要進行肺移植或心肺聯閤移植治療，但由于供體缺乏，大多數患兒隻能通過保守治療延長生存時間。近年來一些臨床研究提示肺動脈高壓靶嚮藥物治療ES有一定效果。現就ES治療的最新進展作一綜述。
애삼만격종합정증피인위시심장외과교치수술적금기증，수요진행폐이식혹심폐연합이식치료，단유우공체결핍，대다수환인지능통과보수치료연장생존시간。근년래일사림상연구제시폐동맥고압파향약물치료ES유일정효과。현취ES치료적최신진전작일종술。
Eisenmenger syndrome (ES) was considered as a surgical contraindication in the past time. Only a few patients got lung transplantations or heart-lung transplantations due to lack of donors. Most of the patients had to choose conservative treatment to prolong their survival time. Recently, some clinical trials indicated targeted therapies in pulmonary arterial hypertension (PAH) were effective for the treatment of ES. This article reviewed the recent advances in this area.
