CAJ | 학술논문

目的：分析气流受限与肺癌危险性的关系。方法对本院新确诊的648例肺癌患者及663例从未患肺癌的患者作为对照组进行对照分析研究。结果合并慢性阻塞性肺疾病的患者，肺癌发生的OR值明显升高，为3．07。当FEV1％＜60％时，肺癌发生的OR值为2．50。当FEV1／FVC％＜50％肺癌发生的OR值为2．77。结论气流受限是肺癌发生的一项独立危险因素，随着肺功能损伤的加重，肺癌发生的危险性明显增高；合并慢性阻塞性肺疾病的患者，肺癌发生的危险性明显增高。
목적：분석기류수한여폐암위험성적관계。방법대본원신학진적648례폐암환자급663례종미환폐암적환자작위대조조진행대조분석연구。결과합병만성조새성폐질병적환자，폐암발생적OR치명현승고，위3．07。당FEV1％＜60％시，폐암발생적OR치위2．50。당FEV1／FVC％＜50％폐암발생적OR치위2．77。결론기류수한시폐암발생적일항독립위험인소，수착폐공능손상적가중，폐암발생적위험성명현증고；합병만성조새성폐질병적환자，폐암발생적위험성명현증고。
[ ABSTRACT] Objective To analyze the relationship between airflow obstruction and the risk of lung cancer . Methods The analysis was based on the data collected in the Second People's Hospital of Weifang .Six hundred and for-ty-eight cases of newly diagnosed patients with lung cancer and 663 patients without lung cancer selected as control group were compared for case-control study .Results The patients with COPD had an increased risk of lung cancer ,OR=3. 07.When FEV1 was lower than 60%,the risk of lung cancer increased (OR=2.50).And when FEV1/FVC was lower than 50%,the risk of lung cancer increased (OR=2.77),too.Conclusion The airflow obstruction is an independent risk factor for lung cancer and the risk of lung cancer can increase obviously with the impairment of lung function ,be-sides patients with a history of COPD have a higher risk of lung cancer .