中国循证心血管医学杂志
中國循證心血管醫學雜誌
중국순증심혈관의학잡지
CHINESE JOURNAL OF EVIDENCE-BASES CARDIOVASCULAR MEDICINE
2015年
1期
108-110
,共3页
赵冰%刘建国%李俊峡%鲍宏刚
趙冰%劉建國%李俊峽%鮑宏剛
조빙%류건국%리준협%포굉강
经皮冠状动脉介入术%桡动脉%止血器
經皮冠狀動脈介入術%橈動脈%止血器
경피관상동맥개입술%뇨동맥%지혈기
Percutaneous coronary intervention%Radial artery%Hemostat
目的:观察急性ST段抬高型心肌梗死患者直接PCI术后采用桡动脉止血器压迫止血的临床效果及安全性。方法选择124例成功进行急诊PCI采用桡动脉径路的患者,术前给予阿司匹林、硫酸氢氯吡格雷,直接PCI术后留置桡动脉鞘管6 h,应用瑞翁株式会社生产的RDP700前臂用直型桡动脉止血器压迫止血,评价其临床效果及安全性,观察性别、年龄、体重及替罗非班对止血器压迫时间及肢体远端肿胀消退时间的影响。结果124例桡动脉径路患者压迫止血器均可于术后即刻成功止血,平均止血压迫时间为(9.9±3.5)h,远端肿胀平均消退时间为(32.4±8.7)h。共有3例(2.4%)发生桡动脉闭塞,5例(4.0%)出现穿刺局部皮肤损害。与男性患者相比,女性患者直接PCI术后桡动脉止血器压迫时间显著延长,撤除止血器后远端组织肿胀消退时间亦明显延长(P均<0.01)。年龄≥60岁、体重<65 kg患者桡动脉止血器压迫时间及远端组织肿胀消退时间较年龄≥60岁、体重≥65 kg明显延长(P均<0.01)。直接PCI术后应用盐酸替罗非班患者桡动脉止血器压迫时间较未应用者显著延长,撤除止血器后远端组织肿胀消退时间亦明显延长(P均<0.01)。结论急诊桡动脉径路行PCI术患者应用桡动脉止血器压迫止血安全有效,性别、年龄、体重及应用盐酸替罗非班影响止血器压迫止血时间及远端组织肿胀消退时间。
目的:觀察急性ST段抬高型心肌梗死患者直接PCI術後採用橈動脈止血器壓迫止血的臨床效果及安全性。方法選擇124例成功進行急診PCI採用橈動脈徑路的患者,術前給予阿司匹林、硫痠氫氯吡格雷,直接PCI術後留置橈動脈鞘管6 h,應用瑞翁株式會社生產的RDP700前臂用直型橈動脈止血器壓迫止血,評價其臨床效果及安全性,觀察性彆、年齡、體重及替囉非班對止血器壓迫時間及肢體遠耑腫脹消退時間的影響。結果124例橈動脈徑路患者壓迫止血器均可于術後即刻成功止血,平均止血壓迫時間為(9.9±3.5)h,遠耑腫脹平均消退時間為(32.4±8.7)h。共有3例(2.4%)髮生橈動脈閉塞,5例(4.0%)齣現穿刺跼部皮膚損害。與男性患者相比,女性患者直接PCI術後橈動脈止血器壓迫時間顯著延長,撤除止血器後遠耑組織腫脹消退時間亦明顯延長(P均<0.01)。年齡≥60歲、體重<65 kg患者橈動脈止血器壓迫時間及遠耑組織腫脹消退時間較年齡≥60歲、體重≥65 kg明顯延長(P均<0.01)。直接PCI術後應用鹽痠替囉非班患者橈動脈止血器壓迫時間較未應用者顯著延長,撤除止血器後遠耑組織腫脹消退時間亦明顯延長(P均<0.01)。結論急診橈動脈徑路行PCI術患者應用橈動脈止血器壓迫止血安全有效,性彆、年齡、體重及應用鹽痠替囉非班影響止血器壓迫止血時間及遠耑組織腫脹消退時間。
목적:관찰급성ST단태고형심기경사환자직접PCI술후채용뇨동맥지혈기압박지혈적림상효과급안전성。방법선택124례성공진행급진PCI채용뇨동맥경로적환자,술전급여아사필림、류산경록필격뢰,직접PCI술후류치뇨동맥초관6 h,응용서옹주식회사생산적RDP700전비용직형뇨동맥지혈기압박지혈,평개기림상효과급안전성,관찰성별、년령、체중급체라비반대지혈기압박시간급지체원단종창소퇴시간적영향。결과124례뇨동맥경로환자압박지혈기균가우술후즉각성공지혈,평균지혈압박시간위(9.9±3.5)h,원단종창평균소퇴시간위(32.4±8.7)h。공유3례(2.4%)발생뇨동맥폐새,5례(4.0%)출현천자국부피부손해。여남성환자상비,녀성환자직접PCI술후뇨동맥지혈기압박시간현저연장,철제지혈기후원단조직종창소퇴시간역명현연장(P균<0.01)。년령≥60세、체중<65 kg환자뇨동맥지혈기압박시간급원단조직종창소퇴시간교년령≥60세、체중≥65 kg명현연장(P균<0.01)。직접PCI술후응용염산체라비반환자뇨동맥지혈기압박시간교미응용자현저연장,철제지혈기후원단조직종창소퇴시간역명현연장(P균<0.01)。결론급진뇨동맥경로행PCI술환자응용뇨동맥지혈기압박지혈안전유효,성별、년령、체중급응용염산체라비반영향지혈기압박지혈시간급원단조직종창소퇴시간。
Objective To observe the clinical efficacy and safety of radial hemostat for pressure hemostasis in patients with acute ST-segment elevation myocardial infarction (STEMI) after direct emergency percutaneous coronary intervention (PCI). Methods The patients (n=124) with successful emergency PCI by radial approach were given aspirin and clopidogrel loading before PCI and radial sheath was kept for 6 h after direct PCI. RDP700 forearm straight radial hemostat (produced by Zeon Corporation) was used for pressure hemostasis, and the clinical efficacy and safety were reviewed. The influences of sex, age, weight and tirofiban on pressure time of hemostat and swelling subsiding time of distal limb were observed. Results All 124 patients had successful immediate hemostasis, and the mean pressure time was (9.9±3.5) h and mean swelling subsiding time of distal limb was (32.4±8.7) h. There were 3 cases (2.4%) had radial occlusion and 5 (4.0%) had skin lesion at puncture focus. Compared with male patients, the pressure time of radial hemostat and swelling subsiding time of distal limb were significantly prolonged (all P<0.01). The pressure time of radial hemostat and swelling subsiding time of distal limb were significantly prolonged in patients aged≥60 and weighed<65 kg (all P<0.01), and also significantly prolonged in patients been given tirofiban compared with those without giving it after direct PCI (all P<0.01). Conclusion The radial hemostat for pressure hemostasis is safe and effective in patients with emergency PCI, and sex, age, weight and tirofiban have influences on pressure time of radial hemostat and swelling subsiding time of distal limb.