CAJ | 학술논문

目的：探讨阿司匹林联合三七制剂对脑梗死复发的干预效果。方法：选取75例脑梗死病人，随机分为两组，对照组单用小剂量肠溶阿司匹林抗凝，治疗组在此基础上加用三七制剂抗凝，观察治疗前后凝血指标、血流变和再梗死率变化，以及出血事件发生率。结果：治疗组纤维蛋白原、PT、APPT、血液黏度及再梗死率与治疗前有显著性差异（P<0.05），且与对照组治疗后比较亦有显著性差异（P<0.05），两组出血事件发生率经比较无显著性差异（P>0.05）。结论：阿司匹林联合三七制剂可延长脑梗死患者凝血时间，改善血液黏度，降低再梗死率。长期服用对脑梗死病人具有协同预防复发作用。
목적：탐토아사필림연합삼칠제제대뇌경사복발적간예효과。방법：선취75례뇌경사병인，수궤분위량조，대조조단용소제량장용아사필림항응，치료조재차기출상가용삼칠제제항응，관찰치료전후응혈지표、혈류변화재경사솔변화，이급출혈사건발생솔。결과：치료조섬유단백원、PT、APPT、혈액점도급재경사솔여치료전유현저성차이（P<0.05），차여대조조치료후비교역유현저성차이（P<0.05），량조출혈사건발생솔경비교무현저성차이（P>0.05）。결론：아사필림연합삼칠제제가연장뇌경사환자응혈시간，개선혈액점도，강저재경사솔。장기복용대뇌경사병인구유협동예방복발작용。
Objective: To investigate intervention effects of Aspirin plus notoginseng pharmaceutics on recurrence of cerebral infarction. Methods: 75 patients were randomly divided into two groups, the control group was given low-dose Aspirin anticoagulant, another was given notoginseng pharmaceutics anticoagulant more. Coagulation, blood flow changes, reinfarction rate and the incidence of bleeding were observed. Results: Compared with before treatment and control group Fibrinogen, PT, APPT, blood viscosity and reinfarction rate in the treatment group was better (P<0.05), while the incidence of bleeding was not statistically significant (P>0.05). Conclusion: Aspirin plus notoginseng pharmaceutics can prolonged clotting time of cerebral infarction patients, blood viscosity was improved, and reinfarction was reduced, and it can prevent cerebral infarction.