CAJ | 학술논문

目的：探讨非介入式前列腺超声联合中西药治疗慢性前列腺炎/慢性骨盆疼痛综合征（CP/CPPS）的临床效果。方法收集临床诊断为CP/CPPS且符合研究标准的患者105例，随机分为3组，每组35例。A组采用非介入式前列腺超声联合中西药治疗方法；B组为中西药物治疗组；C组单用非介入式前列腺超声治疗。观察各组治疗前后前列腺炎症状指数（NIH-CPSI）疼痛或不适症状评分、排尿症状评分、生活质量评分、NIH-CPSI总评分及各组治疗总有效率。结果3组治疗前后NIH-CPSI疼痛或不适症状评分、排尿症状评分、生活质量评分、NIH-CPSI总评分差异比较有统计学意义（P＜0.05）。治疗后，A组分别与B组、C组比较，NIH-CPSI疼痛或不适症状评分、排尿症状评分、生活质量评分、NIH-CPSI总评分差异均具有统计学意义（P＜0.05）；B组与C组比较差异无统计学意义（P＞0.05）。治疗总有效率，A组为88.6%，B组为68.6%，C组为74.3%，A组总有效率最高，A组与B组C组比较差异均具统计学意义（P＜0.05）。结论非介入式前列腺超声与中西药在临床治疗CP/CPPS中具有协同作用，非介入式前列腺超声联合中西药治疗方法能明显改善CP/CPPS患者的NIH-CPSI疼痛或不适症状、排尿症状，提高生活质量。
목적：탐토비개입식전렬선초성연합중서약치료만성전렬선염/만성골분동통종합정（CP/CPPS）적림상효과。방법수집림상진단위CP/CPPS차부합연구표준적환자105례，수궤분위3조，매조35례。A조채용비개입식전렬선초성연합중서약치료방법；B조위중서약물치료조；C조단용비개입식전렬선초성치료。관찰각조치료전후전렬선염증상지수（NIH-CPSI）동통혹불괄증상평분、배뇨증상평분、생활질량평분、NIH-CPSI총평분급각조치료총유효솔。결과3조치료전후NIH-CPSI동통혹불괄증상평분、배뇨증상평분、생활질량평분、NIH-CPSI총평분차이비교유통계학의의（P＜0.05）。치료후，A조분별여B조、C조비교，NIH-CPSI동통혹불괄증상평분、배뇨증상평분、생활질량평분、NIH-CPSI총평분차이균구유통계학의의（P＜0.05）；B조여C조비교차이무통계학의의（P＞0.05）。치료총유효솔，A조위88.6%，B조위68.6%，C조위74.3%，A조총유효솔최고，A조여B조C조비교차이균구통계학의의（P＜0.05）。결론비개입식전렬선초성여중서약재림상치료CP/CPPS중구유협동작용，비개입식전렬선초성연합중서약치료방법능명현개선CP/CPPS환자적NIH-CPSI동통혹불괄증상、배뇨증상，제고생활질량。
Objective To investigate the clinical effects of combination therapy of non-intrusive ultrasound with integrated Chinese-western medcine for patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods A total of 105 cases withCP/CPPS were randomly divided into a combined non-intrusive ultrasound with integrated Chinese-western medcine group (group A, n=35), a Chinese-western medcine group (group B, n=35) and a non-intrusive ultrasound group (group C, n=35). The National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) scores were obtained before and after treatment, and total proportion of effectiveness was evaluated in each group after treatment. Results Obvious differences were found in NIH-CPSI pain score, urinary symptom score ,quality of life score and total NIH-CPSI score before and after treatment in each group (P<0.05). Changes of NIH-CPSI pain score, urinary symptom score , quality of life score and total NIH-CPSI score before and after treatment in group A ,compared with group B and group C respectively ,were statistically significant (P<0.05). The total effective rate was 88.6% in group A, 68.6% in group B and 74.3% in group C. And difference in effective rate in group A, compared with group B (P=0.0098) and group C(P=0.010) respectively ,was significant. Conclusion The non-intrusive ultrasound therapy and the integrated Chinese-western medcine treatment coopetate well in dealing with CP/CPPS. Combination therapy of non-intrusive ultrasound with integrated Chinese-western medcine can improve the quality of living of the CP/CPPS patients by lessening pain and urinary symptoms .