西南国防医药
西南國防醫藥
서남국방의약
MEDICAL JOURNAL OF NATIONAL DEFENDING FORCES IN SOUTHWEST CHINA
2015年
2期
119-122
,共4页
娄国平%李显东%张昭勇%曹政
婁國平%李顯東%張昭勇%曹政
루국평%리현동%장소용%조정
甲状腺%甲状旁腺素%血钙%低钙血症%术后%预测
甲狀腺%甲狀徬腺素%血鈣%低鈣血癥%術後%預測
갑상선%갑상방선소%혈개%저개혈증%술후%예측
thyroid%parathyroid hormone%serum calcium%hypocalcemia%postoperation%prediction
目的：观察甲状腺术后血清甲状旁腺素（ PTH）及Ca水平与患者症状性低钙血症发生之间关系，并探讨其预测价值。方法选择本院于2011年1月~2013年12月收治的需行甲状腺全切除术患者180例作为研究对象，男67例，女113例，观察术后1、12、24 h的血清Ca及PTH水平，统计术后症状性低钙血症发生率，分析术后血清Ca及PTH水平与症状性低钙血症发生之间的关系。结果本组180例中，术后出现症状性低钙血症67例，发生率为37.2%；术后血清钙浓度<2.2 mmol/L患者有75例，其中出现症状性低钙血症64例（85.3%），而术后血钙正常患者105例，出现症状性低钙血症仅3例（2.9%）（p<0.05）。术后PTH<1.48 pmol/L患者共77例，出现症状性低钙血症61例（79.2%），而PTH>1.48 pmol/L患者103例，出现症状性低钙血症仅6例（5.9%）（p<0.05）。结论甲状腺术后血清PTH及Ca水平与患者症状性低钙血症发生具有相关性，监测术后血清PTH及Ca水平具有重要临床预测价值。
目的：觀察甲狀腺術後血清甲狀徬腺素（ PTH）及Ca水平與患者癥狀性低鈣血癥髮生之間關繫，併探討其預測價值。方法選擇本院于2011年1月~2013年12月收治的需行甲狀腺全切除術患者180例作為研究對象，男67例，女113例，觀察術後1、12、24 h的血清Ca及PTH水平，統計術後癥狀性低鈣血癥髮生率，分析術後血清Ca及PTH水平與癥狀性低鈣血癥髮生之間的關繫。結果本組180例中，術後齣現癥狀性低鈣血癥67例，髮生率為37.2%；術後血清鈣濃度<2.2 mmol/L患者有75例，其中齣現癥狀性低鈣血癥64例（85.3%），而術後血鈣正常患者105例，齣現癥狀性低鈣血癥僅3例（2.9%）（p<0.05）。術後PTH<1.48 pmol/L患者共77例，齣現癥狀性低鈣血癥61例（79.2%），而PTH>1.48 pmol/L患者103例，齣現癥狀性低鈣血癥僅6例（5.9%）（p<0.05）。結論甲狀腺術後血清PTH及Ca水平與患者癥狀性低鈣血癥髮生具有相關性，鑑測術後血清PTH及Ca水平具有重要臨床預測價值。
목적：관찰갑상선술후혈청갑상방선소（ PTH）급Ca수평여환자증상성저개혈증발생지간관계，병탐토기예측개치。방법선택본원우2011년1월~2013년12월수치적수행갑상선전절제술환자180례작위연구대상，남67례，녀113례，관찰술후1、12、24 h적혈청Ca급PTH수평，통계술후증상성저개혈증발생솔，분석술후혈청Ca급PTH수평여증상성저개혈증발생지간적관계。결과본조180례중，술후출현증상성저개혈증67례，발생솔위37.2%；술후혈청개농도<2.2 mmol/L환자유75례，기중출현증상성저개혈증64례（85.3%），이술후혈개정상환자105례，출현증상성저개혈증부3례（2.9%）（p<0.05）。술후PTH<1.48 pmol/L환자공77례，출현증상성저개혈증61례（79.2%），이PTH>1.48 pmol/L환자103례，출현증상성저개혈증부6례（5.9%）（p<0.05）。결론갑상선술후혈청PTH급Ca수평여환자증상성저개혈증발생구유상관성，감측술후혈청PTH급Ca수평구유중요림상예측개치。
Objective To observe the relation of serum parathyroid hormone( PTH )and serum calcium( Ca )level with the incidence of symptomatic hypocalcemia in the patients after thyroid operation and explore the predictive value. Methods Total 180 patients to receive thyroid operation in our hospital from Jan. 2011 to Dec. 2013 were selected as research subjects(male n=67,female n=113);the serum Ca and PTH levels one hour,12 hours,and 24 hours after the operation were measured,statistics of the incidences of postoperative symptomatic hypocalcemia was made,and the relationship between the postoperative serum Ca and PTH levels and symptomatic hypocalcemia was analyzed. Resuits In 180 cases,postoperative symptomatic hypocalcemia occurred in 67 cases,with an incidence of 37. 2%;the postoperative serum calcium concentration was less than 2. 2 mmol/L in 75 cases,including 64 ones(85. 3%) with symptomatic hypocalcemia,while postoperative serum calcium concentration was normal in 105 cases,including 3 ones(2. 9%) with symptomatic hypocalcemia( p <0. 05 ). After the operation,PTH of 77 cases was less than 1. 48 pmol/L including 61 ones (79. 2%)with symptomatic hypocalcemia and 103 ones was larger than 1. 48 pmol/L including six ones(5. 9%)with symptomatic hypocalcemia(p<0. 05). Conciusion The postoperative serum PTH and Ca levels after thyroid operation have correlation with the incidence of symptomatic hypocalcemia,so monitoring of postoperative serum PTH and Ca levels has significant predictive value for clinical use.
