CAJ | 학술논문

目的：观察阿莫西林联合叶酸治疗慢性萎缩性胃炎的临床疗效.方法：将70例确诊为慢性萎缩性胃炎患者随机分为2组，对照组35例给予口服叶酸治疗，实验组35例在叶酸治疗的基础上同时给予口服阿莫西林，2组均连续用药2周，观察2组患者治疗前后的临床症状、病理形态学及胃镜下的变化.结果：实验组的临床症状缓解率、病理检查好转总有效率和胃镜下表现好转总有效率分别为91.4%、85.7%和80.0%，对照组则分别为71.4%、62.9%和57.1%，两组比较差异有统计学意义(P<0.01).结论：阿莫西林联合叶酸比单独叶酸治疗慢性萎缩性胃炎的疗效更好.
목적：관찰아막서림연합협산치료만성위축성위염적림상료효.방법：장70례학진위만성위축성위염환자수궤분위2조，대조조35례급여구복협산치료，실험조35례재협산치료적기출상동시급여구복아막서림，2조균련속용약2주，관찰2조환자치료전후적림상증상、병리형태학급위경하적변화.결과：실험조적림상증상완해솔、병리검사호전총유효솔화위경하표현호전총유효솔분별위91.4%、85.7%화80.0%，대조조칙분별위71.4%、62.9%화57.1%，량조비교차이유통계학의의(P<0.01).결론：아막서림연합협산비단독협산치료만성위축성위염적료효경호.
Objective: To observe the clinical curative effect of amoxicillin combined with folic acid in treatment of chronic atrophic gastritis. Methods: 70 cases of chronic atrophic gastritis patients were randomly divided into two groups. The control group was treated with folic acid while the experimental group received folic acid and amoxicillin. The clinical symptoms, pathological and endoscopy changes were observed after two weeks of the treatment. Results: The clinical remission rate, total efficiency of pathology and improvement performance in endoscopy of the experimental group were 91.4%, 85.7% and 80.0%, respectively, which were higher than that of the control group 71.4%, 62.9% and 57.1%, respectively(P<0.01). Conclusion: Amoxicillin combined with folic acid was more effective for the treatment of chronic atrophic gastritis than only using folic acid.