CAJ | 학술논문

目的：回顾近10年成都战区部分官兵幽门螺杆菌（ Hp）感染特点及其与上消化道疾病的关系，以指导Hp相关胃肠疾病的诊治。方法收集2005年1月~2015年1月在我院就诊的成都战区军人Hp感染患者病例资料，分析Hp感染特点及与上消化道疾病的关系。结果共纳入1248例因上消化道症状、需做胃镜检查患者，其中男性1104例，女性144例；年龄16~88（34.1±15.3）岁。男性Hp阳性者564例，感染率为51.1%；女性Hp阳性者85例，感染率为59.0%，男女Hp感染率无显著差异（ p>0.05）。内镜下诊断：慢性胃炎（包括慢性非萎缩性胃炎及慢性萎缩性胃炎）962例，Hp阳性者483例。其中慢性非萎缩性胃炎伴糜烂143例，Hp阳性者79例；慢性萎缩性胃炎32例，Hp阳性者12例；消化性溃疡251例，Hp阳性者173例（68.9%），Hp阴性者78例，两者有显著差异（ p<0.01）。病理检查：胃癌2例，Hp阳性者0例；没有不典型增生；肠化3例，Hp阳性者1例，Hp阴性者2例。结论本战区军人Hp感染率高（52.0%），影响官兵健康，应引起高度重视。Hp感染与消化性溃疡密切相关。
목적：회고근10년성도전구부분관병유문라간균（ Hp）감염특점급기여상소화도질병적관계，이지도Hp상관위장질병적진치。방법수집2005년1월~2015년1월재아원취진적성도전구군인Hp감염환자병례자료，분석Hp감염특점급여상소화도질병적관계。결과공납입1248례인상소화도증상、수주위경검사환자，기중남성1104례，녀성144례；년령16~88（34.1±15.3）세。남성Hp양성자564례，감염솔위51.1%；녀성Hp양성자85례，감염솔위59.0%，남녀Hp감염솔무현저차이（ p>0.05）。내경하진단：만성위염（포괄만성비위축성위염급만성위축성위염）962례，Hp양성자483례。기중만성비위축성위염반미란143례，Hp양성자79례；만성위축성위염32례，Hp양성자12례；소화성궤양251례，Hp양성자173례（68.9%），Hp음성자78례，량자유현저차이（ p<0.01）。병리검사：위암2례，Hp양성자0례；몰유불전형증생；장화3례，Hp양성자1례，Hp음성자2례。결론본전구군인Hp감염솔고（52.0%），영향관병건강，응인기고도중시。Hp감염여소화성궤양밀절상관。
Objective To review the characteristics of Helicobacter pylori(Hp)infection of the officers and soldiers in Chengdu Military Region in the last 10 years and the relation between Hp infection and upper gastrointestinal diseases,so as to provide guidance for treatment of Hp-related gastrointestinal diseases. Methods The clinical data on the Hp-infected officer and soldier patients in Chengdu Military Region to receive treatment in our hospital from Jan. 2005 to Jan. 2015 were collected in order to analyze the characteristics of Hp infection and the relation between Hp infection and upper gastrointestinal diseases. Resuits Total 1248 patients with upper gastrointestinal symptoms to receive gastroscopy examination were selected,including 1104 males and 144 females,who were all aged 16~88,averagely(34. 1 ± 15. 3)years old. 30 years old were taken as the median. Among the male patients,564 ones were Hp positive,with an infection rate of 51. 1%;among the female patients,85 ones were Hp positive,with an infection rate of 59. 0%. There was no significant difference of the Hp infection rates between the males and females(p>0. 05). Endoscopic diagnosis:chronic gastritis ( including chronic non-atrophic gastritis and chronic atrophic gastritis)in 962 cases,and Hp positive in 483 cases,including:chronic non-atrophic gastritis with erosion in 143 cases( Hp positive in 79 cases );chronic atrophic gastritis in 32 cases( Hp positive in 12 cases);peptic ulcer in 251 cases(Hp positive in 173 cases,68. 9%;Hp negative in 78 cases). The values had a significant difference ( p < 0. 01 ). Pathological examination:gastric cancer in two cases,no Hp positive;there was not typical hyperplasia;intestinal metaplasia in three cases,including Hp positive in one case and Hp negative in two cases. Conciusion In this military region,Hp infection rate is high(52. 0%),which will affect the officers and soldiers′health,so attention should be paid. Hp infection is closely related to peptic ulcer.