医学与哲学
醫學與哲學
의학여철학
MEDICINE AND PHILOSOPHY
2015年
2期
31-32
,共2页
前哨淋巴结活检%吲哚菁绿荧光导航%亚甲蓝染色法
前哨淋巴結活檢%吲哚菁綠熒光導航%亞甲藍染色法
전초림파결활검%신타정록형광도항%아갑람염색법
sentinel lymph node biopsy%indocyanine green%fluorescence imaging Blue dye
通过对比吲哚菁绿（ICG）与亚甲蓝两种染色剂在前哨淋巴结活检（SLNB）中的应用，来证实ICG荧光示踪法在SL‐NB中的优势。选取我院从2010年到2012年68位行SLNB的乳腺癌患者，随机分成两组，一组采用ICG荧光导航SL‐NB ，共36例，另一组采用亚甲蓝染料法SLNB ，共32例，SLNB结束后行腋窝淋巴结清扫（ALND），计算两组的前哨淋巴结（SLN）检出成功率，敏感度、假阴性率。结果显示，前者的SLN检出成功率高于后者（97．2％ vs ．81．3％，P＜0．05），二者的敏感度、假阴性率大致相似（敏感度94．7％ vs ．93．3％，假阴性率5．3％ vs ．6．6％）。因此，ICG荧光导航在SLNB中成功率高于亚甲蓝染色法。
通過對比吲哚菁綠（ICG）與亞甲藍兩種染色劑在前哨淋巴結活檢（SLNB）中的應用，來證實ICG熒光示蹤法在SL‐NB中的優勢。選取我院從2010年到2012年68位行SLNB的乳腺癌患者，隨機分成兩組，一組採用ICG熒光導航SL‐NB ，共36例，另一組採用亞甲藍染料法SLNB ，共32例，SLNB結束後行腋窩淋巴結清掃（ALND），計算兩組的前哨淋巴結（SLN）檢齣成功率，敏感度、假陰性率。結果顯示，前者的SLN檢齣成功率高于後者（97．2％ vs ．81．3％，P＜0．05），二者的敏感度、假陰性率大緻相似（敏感度94．7％ vs ．93．3％，假陰性率5．3％ vs ．6．6％）。因此，ICG熒光導航在SLNB中成功率高于亞甲藍染色法。
통과대비신타정록（ICG）여아갑람량충염색제재전초림파결활검（SLNB）중적응용，래증실ICG형광시종법재SL‐NB중적우세。선취아원종2010년도2012년68위행SLNB적유선암환자，수궤분성량조，일조채용ICG형광도항SL‐NB ，공36례，령일조채용아갑람염료법SLNB ，공32례，SLNB결속후행액와림파결청소（ALND），계산량조적전초림파결（SLN）검출성공솔，민감도、가음성솔。결과현시，전자적SLN검출성공솔고우후자（97．2％ vs ．81．3％，P＜0．05），이자적민감도、가음성솔대치상사（민감도94．7％ vs ．93．3％，가음성솔5．3％ vs ．6．6％）。인차，ICG형광도항재SLNB중성공솔고우아갑람염색법。
Compare the usefulness of ICG against the current using method , namely the blue dye tracer , to determine whether this can overcome the shortcoming of the blue dye method in breast cancer SLNB .From 2010 to 2012 ,68 consecutive patients were diagnosed with breast cancer underwent SLNB in our hospital .Patients were randomized to either ICG fluorescence or blue dye group for SLNB .All women had a level Ⅰ and Ⅱ axillary dissection after the SLNB . ICG fluorescence was used in 36 women and 32 had blue dye .Baseline demographic data were similar in the two cohorts . The detection rate of SLNB with ICG fluorescence was higher than with blue dye (97 .2% vs .81 .3% , P<0 .05) .The sensitivity ,false‐negative rate and means number of excised SLNs were similar (sensitivity 94 .7% for ICG fluorescence vs .93 .3% for blue dye ;false‐negative rate 5 .3% vs .6 .6% ) .ICG fluorescence was superior to blue dye in identification of the SLN ,but the sensitivity ,false‐negative rate and means number of excised SLNs were similar .
