CAJ | 학술논문

目的：探讨磁共振张量成像（DTI）在婴幼儿脑瘫诊断中的应用价值。方法选取33例脑瘫婴幼儿作为脑瘫组，33例正常婴幼儿作为对照组，分别对其行DTI检查。观察神经纤维束的改变，研究DTI成像特点及其与脑瘫的相关性，并采用统计学方法比较脑瘫组和对照组感兴趣区的各向异性（FA）值。结果33例脑瘫患儿中，23例伴有不同部位和不同程度的神经纤维束稀疏、中断及走行异常，10例患儿神经纤维束改变不明显；脑瘫组患儿感兴趣区的FA值较低，与对照组相比有显著差异（P<0.05）。结论DTI异常表现与脑性瘫痪具有相关性，DTI检查有助于对婴幼儿脑瘫做出早期诊断，为制定合理的诊疗方案提供依据。
목적：탐토자공진장량성상（DTI）재영유인뇌탄진단중적응용개치。방법선취33례뇌탄영유인작위뇌탄조，33례정상영유인작위대조조，분별대기행DTI검사。관찰신경섬유속적개변，연구DTI성상특점급기여뇌탄적상관성，병채용통계학방법비교뇌탄조화대조조감흥취구적각향이성（FA）치。결과33례뇌탄환인중，23례반유불동부위화불동정도적신경섬유속희소、중단급주행이상，10례환인신경섬유속개변불명현；뇌탄조환인감흥취구적FA치교저，여대조조상비유현저차이（P<0.05）。결론DTI이상표현여뇌성탄탄구유상관성，DTI검사유조우대영유인뇌탄주출조기진단，위제정합리적진료방안제공의거。
Objective To explore the significance of applying DTI (Diffusion Tensor Imaging) in the diagnosis of cerebral palsy in infants with developmental delays. Methods Thirty-three cases of cerebral palsy infants were selected as the cerebral palsy group, while 33 cases of healthy children as the control group. Then, DTI was performed on both the groups so as to observe the changes of the ifber tracts and research DTI features and its relevance with cerebral palsy. Additionally, the statistical method was applied to compare each FA (Fractional Anisotropy) value in the ROIs (Region-of-Interest) between the cerebral palsy group and the control group. Results Of 33 cerebral palsy infants, sparse and interrupted ifber tracts with abnormal orientation were revealed in different extent in 23 cases on different regions;no obvious changes of ifber tracts were revealed in 10 cases. The FA value in the ROIs of the cerebral palsy group was lower than that of the control group. There were significant differences (P<0.05) between the two groups. Conclusion Abnormalities revealed by DTI were correlated with cerebral palsy. As an useful method for diagnosis of cerebral palsy in infants and young children with developmental delays, DTI can provide the basis for clinicians to make reasonable treatment plan.