CAJ | 학술논문

目的：：探讨桂枝去桂加茯苓白术汤治疗急性肾损伤的临床效果。方法：通过选取临床诊断为AKI的患者60例,采用随机原则把患者分为实验组( A组)和对照组( B组),并按照 AKI分级标准将两组患者各分为三级,分别为：A1组、A2组、A3组与B1组、B2组、B3组,每小组10人,通过跟踪监测血清尿素氮( BUN)、肌酐( Cr),对比观察桂枝去桂加茯苓白术汤治疗和常规治疗的临床疗效。结果：在治疗组中,血清BUN和Cr呈下降趋势,对照组下降不明显。同级实验组和对照组比较,其组间比较BUN、Cr水平均差异有统计学意义(P<0.05),治疗时间对BUN、Cr影响仅A3组与B3组差异有统计学意义(P<0.05)。时间和治疗因素的交互影响中,仅A3组与B3组间的BUN水平差异无统计学意义(P>0.05),其余各比较组间的BUN、Cr水平均差异有统计学意义(P<0.05)。结论：急性肾损伤患者在常规治疗基础上,加用桂枝去桂加茯苓白术汤,能在较短时间内明显降低BUN和Cr,促进肾功能恢复。
목적：：탐토계지거계가복령백술탕치료급성신손상적림상효과。방법：통과선취림상진단위AKI적환자60례,채용수궤원칙파환자분위실험조( A조)화대조조( B조),병안조 AKI분급표준장량조환자각분위삼급,분별위：A1조、A2조、A3조여B1조、B2조、B3조,매소조10인,통과근종감측혈청뇨소담( BUN)、기항( Cr),대비관찰계지거계가복령백술탕치료화상규치료적림상료효。결과：재치료조중,혈청BUN화Cr정하강추세,대조조하강불명현。동급실험조화대조조비교,기조간비교BUN、Cr수평균차이유통계학의의(P<0.05),치료시간대BUN、Cr영향부A3조여B3조차이유통계학의의(P<0.05)。시간화치료인소적교호영향중,부A3조여B3조간적BUN수평차이무통계학의의(P>0.05),기여각비교조간적BUN、Cr수평균차이유통계학의의(P<0.05)。결론：급성신손상환자재상규치료기출상,가용계지거계가복령백술탕,능재교단시간내명현강저BUN화Cr,촉진신공능회복。
Objective:The aim of this study was to investigate the clinical effects of Guizhi Qu Gui Jia Fuling Baizhu Tang on acute kidney injury( AKI) in admitted patients. Methods:60 patients of AKI were enrolled who were randomly divided into treat-ment( A group) and control( B group) groups. The groups each other were eventually falled into three grades by the grading standards of AKI, then the groups followed as A1, A2, A3 and B1, B2, B3 groups. There were 10 patients in each group. We estimated the clinical effects of Guizhi Qu Gui Jia Fuling Baizhu Tang and the routine treatment by detecting BUN and Cr in blood serum. Results:The levels of BUN and Cr were decreased obviously in the treatment groups, but the control groups were not. BUN and Cr levels were significantly different in the same grade (P<0. 05). The effects of therapy times on the levels of BUN and Cr were significant in A3 and B3 groups. The differences of the interaction of time and treatment were statistical significance among other compared groups, ex-cept for A3 and B3 groups. Conclusion:Adding Guizhi Qu Gui Jia Fuling Baizhu Tang on the base of the routine treatment could de-crease the levels of BUN and Cr in short time and promoted kidney function recovery from AKI.