CAJ | 학술논문

目的分析总结胃神经鞘瘤的临床特点、诊断及治疗方法。方法回顾性分析我们于2000年1月至2013年12月间收治的21例胃神经鞘瘤的临床病例资料，回顾参数包括一般资料统计、临床表现、诊断方法及治疗方法等。结果主要临床表现为腹痛、腹部肿块和上消化道出血。术前经 B 超、上消化道钡剂造影、胃镜、CT 及超声内镜检查，仅确诊2例，余均误诊。本组均手术治疗，行胃局部切除术6例，胃大部分切除术13例，根治性胃次全切术2例。2例恶性胃神经鞘瘤病人分别于术后14个月和36个月死于肺转移，良性者效果良好。结论胃神经鞘瘤是一种比较罕见的间质源性肿瘤，临床表现缺乏特异性，术前确诊率低，临床上以良性多见，该病对化疗、放疗不敏感，手术切除是治疗的唯一方法。
목적분석총결위신경초류적림상특점、진단급치료방법。방법회고성분석아문우2000년1월지2013년12월간수치적21례위신경초류적림상병례자료，회고삼수포괄일반자료통계、림상표현、진단방법급치료방법등。결과주요림상표현위복통、복부종괴화상소화도출혈。술전경 B 초、상소화도패제조영、위경、CT 급초성내경검사，부학진2례，여균오진。본조균수술치료，행위국부절제술6례，위대부분절제술13례，근치성위차전절술2례。2례악성위신경초류병인분별우술후14개월화36개월사우폐전이，량성자효과량호。결론위신경초류시일충비교한견적간질원성종류，림상표현결핍특이성，술전학진솔저，림상상이량성다견，해병대화료、방료불민감，수술절제시치료적유일방법。
Objective To explore the clinical characteristics,diagnosis and treatment of gastric schwannomas.Methods The clinical data of 21 patients of gastric schwannomas were retrospectively analyzed from January 2000 to December 2013.Results Their clinical manifestations included abdomi-nal pain,abdominal mass and upper gastrointestinal hemorrhage.The preoperative diagnosis was based on type B ultrasound,barium enema,gastroscope,computed tomography (CT)and endoscopic ultrasound (EUS).Only 2 cases were corrected diagnosed while the remainder all misdiagnosed.All patients underwent the procedures of gastric resection (n=6),subtotal resection (n=13)and radical subtotal gastrectomy (n=2).Two patients with malignant gastric schwannomas died of postoperative pulmonary metastasis at 14 and 36 months respectively.The operative outcomes of benign gastric schwannomas were generally fair.Conclusions Gastric schwannomas are rare mesenchymal tumors with non-specific clinical features and low rates of preoperative diagnosis.Most tumors are benign and insensitive to chemo radiotherapy.Operation is the only curative treatment.