CAJ | 학술논문

目的探讨经肝动脉化疗栓塞(TACE)联合超声引导下射频消融(RFA)治疗原发性肝癌的疗效。方法对2013年1月至2014年5月行 TACE 联合 RFA 治疗的81例中晚期原发性肝癌病人资料进行回顾性分析,并与同期单独行 TACE 的99例中晚期原发性肝癌病人进行疗效比较。结果TACE 联合 RFA 治疗的中晚期原发性肝癌病人疗效明显好于单纯行 TACE 组病人,TACE联合 RFA 组在肿瘤的疾病控制率(93.8%)、完全缓解率(13.6%)及部分缓解率(44.4%)均优于单纯行 TACE 组(76.8%、5.1%、30.3%),P <0.05；AFP 下降水平也优于单纯行 TACE 组(P <0.05)。结论TACE 联合 RFA 治疗中晚期原发性肝癌疗效好,可做临床推广。
목적탐토경간동맥화료전새(TACE)연합초성인도하사빈소융(RFA)치료원발성간암적료효。방법대2013년1월지2014년5월행 TACE 연합 RFA 치료적81례중만기원발성간암병인자료진행회고성분석,병여동기단독행 TACE 적99례중만기원발성간암병인진행료효비교。결과TACE 연합 RFA 치료적중만기원발성간암병인료효명현호우단순행 TACE 조병인,TACE연합 RFA 조재종류적질병공제솔(93.8%)、완전완해솔(13.6%)급부분완해솔(44.4%)균우우단순행 TACE 조(76.8%、5.1%、30.3%),P <0.05；AFP 하강수평야우우단순행 TACE 조(P <0.05)。결론TACE 연합 RFA 치료중만기원발성간암료효호,가주림상추엄。
Objective To explore the efficacies of transcatheter hepatic arterial chemoemboliza-tion (TACE)plus ultrasound-guided radiofrequency ablation (RFA)in the treatment of advanced hep-atocellular carcinoma (HCC).Methods From January 2013 to May 2014,81 patients with advanced HCC underwent TACE plus ultrasound-guided RFA.And their efficacies were compared with 99 counterparts with advanced HCC undergoing TACE alone.The clinical data of these patients were an-alyzed retrospectively.Results Compared to TACE alone ,TACE plus RFA demonstrated statistical-ly significant benefits in disease control rate,complete remission rate,partial remission rate and a de-cline of alpha fetal protein (AFP).Conclusions Compared to TACE alone,TACE plus RFA offers better therapeutic efficacies for advanced HCC.