CAJ | 학술논문

研究白藜芦醇对大鼠血清指标及肝指数的影响，探讨白藜芦醇对肝损伤大鼠的保护作用．将72只雄性大鼠随机分为6组，空白对照组、模型对照组、低、中、高剂量组和阳性药物对照组．连续给药30 d后称取大鼠重量，取血清分别检测血清谷草转氨酶（ AST）、谷丙转氨酶（ ALT）和超氧化物歧化酶（ SOD）、丙二醛（ MDA）含量，并测定肝指数、肾指数、脾指数．结果表明，白藜芦醇能降低大鼠血清中ALT、AST、TG的水平（P＜0．05），提高了SOD的含量、降低了MDA的含量（P＜0．05）．说明白藜芦醇具有降低大鼠ALT、AST的作用，对肝损伤大鼠具有肝保护作用．
연구백려호순대대서혈청지표급간지수적영향，탐토백려호순대간손상대서적보호작용．장72지웅성대서수궤분위6조，공백대조조、모형대조조、저、중、고제량조화양성약물대조조．련속급약30 d후칭취대서중량，취혈청분별검측혈청곡초전안매（ AST）、곡병전안매（ ALT）화초양화물기화매（ SOD）、병이철（ MDA）함량，병측정간지수、신지수、비지수．결과표명，백려호순능강저대서혈청중ALT、AST、TG적수평（P＜0．05），제고료SOD적함량、강저료MDA적함량（P＜0．05）．설명백려호순구유강저대서ALT、AST적작용，대간손상대서구유간보호작용．
To study the effects of resveratrol on serum indicators and hepatic index in rats, and investigate the protective effect of resveratrol on hepatic injury rats 72 male rats were randomly divided into a blank control group,model control group, resveratrol high,middle, low dosage group and positive drug control group.After 30 days of administration, rats were weighted.The serum was collected to detect glutamic-oxaloacetic transaminase(AST),ala-nine aminotransferase(ALT), superoxide dismutase(SOD), malondialdehyde(MDA), liv-ing index,kidney index and spleen index.The results showed that Resveratrol could reduce rats serum ALT,AST,TG levels(P<0.05),increased the content of SOD,and reduced the content of MDA(P<0.05).Resveratrol has the ability decreasing rats’ ALT and AST,and the protective effect on liver injury rats.