CAJ | 학술논문

超声分子成像是基于靶向超声造影剂发展起来的一门新兴的影像技术，通过超声造影的方式反映细胞的病理生理变化，在分子水平上显示疾病发生、发展的过程。近年来，出现了多种用于超声分子成像的聚乳酸-乙醇酸造影剂。本文就这些新兴造影剂的制备方法和靶向设计做一综述。
초성분자성상시기우파향초성조영제발전기래적일문신흥적영상기술，통과초성조영적방식반영세포적병리생리변화，재분자수평상현시질병발생、발전적과정。근년래，출현료다충용우초성분자성상적취유산-을순산조영제。본문취저사신흥조영제적제비방법화파향설계주일종술。
Ultrasound molecular imaging is based on targeted contrast agents, and reflects cells, physiological and pathological changes through ultrasound. Besides, it also displays the progress of disease occurrence and development at the molecular level. There are many novel ultrasound PLGA contrast agents in recent years. The aim of this review is to introduce the progress of preparation and targeting design of these agents.