癫癎与神经电生理学杂志
癲癎與神經電生理學雜誌
전간여신경전생이학잡지
JOURNAL OF EPILEPTOLOGY AND ELECTRONEUROPHYSIOLOGY(CHINA)
2015年
1期
14-18
,共5页
伴中央颞区棘波良性癫癎(BECT)%睡眠期癫癎性电持续状态(ESES)%卡马西平(CBZ)
伴中央顳區棘波良性癲癎(BECT)%睡眠期癲癎性電持續狀態(ESES)%卡馬西平(CBZ)
반중앙섭구극파량성전간(BECT)%수면기전간성전지속상태(ESES)%잡마서평(CBZ)
BECT%ESES%CBZ
目的：探讨卡马西平（CBZ）诱导儿童伴中央中颞区棘波的良性癫癎（BECT ）发生睡眠期癫癎性电持续状态（ESES）的相关因素。方法：回顾分析219例BECT治疗过程中6例出现ESES的病历资料。结果：CBZ治疗组123例中有6例出现ESES ，非CBZ治疗组96例中无ESES发生，两组发生率比较差异有统计学意义。6例ESES中，有5例出现于Rolandio区棘波组，1例出现于非棘波组，两组发生率比较差异有统计学意义。结论：CBZ能导致BECT 出现ESES现象，Rolando区棘波与 ESES的发生有一定相关性。
目的：探討卡馬西平（CBZ）誘導兒童伴中央中顳區棘波的良性癲癎（BECT ）髮生睡眠期癲癎性電持續狀態（ESES）的相關因素。方法：迴顧分析219例BECT治療過程中6例齣現ESES的病歷資料。結果：CBZ治療組123例中有6例齣現ESES ，非CBZ治療組96例中無ESES髮生，兩組髮生率比較差異有統計學意義。6例ESES中，有5例齣現于Rolandio區棘波組，1例齣現于非棘波組，兩組髮生率比較差異有統計學意義。結論：CBZ能導緻BECT 齣現ESES現象，Rolando區棘波與 ESES的髮生有一定相關性。
목적：탐토잡마서평（CBZ）유도인동반중앙중섭구극파적량성전간（BECT ）발생수면기전간성전지속상태（ESES）적상관인소。방법：회고분석219례BECT치료과정중6례출현ESES적병력자료。결과：CBZ치료조123례중유6례출현ESES ，비CBZ치료조96례중무ESES발생，량조발생솔비교차이유통계학의의。6례ESES중，유5례출현우Rolandio구극파조，1례출현우비극파조，량조발생솔비교차이유통계학의의。결론：CBZ능도치BECT 출현ESES현상，Rolando구극파여 ESES적발생유일정상관성。
Objective:To explore the correlation of carbamazepine (CBZ) with occurrence of electri‐cal status epilepticus during sleep ( ESES) in benign epilepsy with centrotemporal spikes (BECT) .Meth‐ods:The clinical data of 6 patients with ESES out of 219 patients with BECT in our hospital were analyzed retrospectively .Results:The onset age of 219 children ranged from 4 years to 12 years .6 cases wilh ESES were found in 123 patients with CBZ(CBZ group) .No patient who was treated with valproate or topira‐mate showed ESES in 96 patients(non‐CBZ group) .There was a significant difference between CBZ group and non‐CBZ group(P<0 .05) .The duration of ESES disappearence in EEG examination ranged between 3 and 6 months after discontinuation of CBZ ..Five cases in 6 patients with ESES suffered from centro‐temporal spikes .Conclusion:CBZ can induce ESES in the treatment of BECT ,although it rarely happens . There is a certain correlation between ESES and BECT with spike waves in rolandic area .
