肿瘤预防与治疗
腫瘤預防與治療
종류예방여치료
JOURNAL OF CANCER CONTROL AND TREATMENT
2015年
1期
22-25,26
,共5页
宫颈浸润癌%癌前病变%筛查%发病率%高发年龄
宮頸浸潤癌%癌前病變%篩查%髮病率%高髮年齡
궁경침윤암%암전병변%사사%발병솔%고발년령
Invasive Carcinoma of Cervix%Cervical Precancerous Lesions%Screening%Incidence of Disease%Par-oxysmal Age
目的：：探讨宫颈浸润癌及癌前病变与女性年龄的关系。方法：2013年45430例已婚妇女在天津金域医学检验中心进行了宫颈浸润癌筛查。首先进行TCT检测,然后对TCT检测结果阳性病例行HC2HPV-DNA检测,两项结果为阳性者,行阴道镜及宫颈活检。对检测结果按照年龄分组进行统计分析。结果：45430例中,AS-CUS及以上者共2234例(4．92%),而30~39岁组、40~49岁组及50~59岁组的发病率较高。2234例中HC2HPV-DNA阳性者1572例(70．37%)。20~29岁组HPV感染率最高,占该年龄段ASCUS及以上者总人数的83．52%。宫颈浸润癌及癌前病变发病率分别为0．16%及1．55%,其中40~49岁组及50~59岁组宫颈浸润癌发病率最高,均为0．28%,远高于其他年龄组,差异有统计学意义( P<0．05)。30~39岁组及40~49岁组的癌前病变发病率分别是1．86%和1．82%,远高于其他年龄组,差异有统计学意义( P<0．05)。与宫颈浸润癌高发年龄相比,癌前病变高发年龄明显提前。结论：天津市已婚妇女的癌前病变的高发年龄为30~49岁,而宫颈浸润癌的高发年龄为40~59岁。
目的：：探討宮頸浸潤癌及癌前病變與女性年齡的關繫。方法：2013年45430例已婚婦女在天津金域醫學檢驗中心進行瞭宮頸浸潤癌篩查。首先進行TCT檢測,然後對TCT檢測結果暘性病例行HC2HPV-DNA檢測,兩項結果為暘性者,行陰道鏡及宮頸活檢。對檢測結果按照年齡分組進行統計分析。結果：45430例中,AS-CUS及以上者共2234例(4．92%),而30~39歲組、40~49歲組及50~59歲組的髮病率較高。2234例中HC2HPV-DNA暘性者1572例(70．37%)。20~29歲組HPV感染率最高,佔該年齡段ASCUS及以上者總人數的83．52%。宮頸浸潤癌及癌前病變髮病率分彆為0．16%及1．55%,其中40~49歲組及50~59歲組宮頸浸潤癌髮病率最高,均為0．28%,遠高于其他年齡組,差異有統計學意義( P<0．05)。30~39歲組及40~49歲組的癌前病變髮病率分彆是1．86%和1．82%,遠高于其他年齡組,差異有統計學意義( P<0．05)。與宮頸浸潤癌高髮年齡相比,癌前病變高髮年齡明顯提前。結論：天津市已婚婦女的癌前病變的高髮年齡為30~49歲,而宮頸浸潤癌的高髮年齡為40~59歲。
목적：：탐토궁경침윤암급암전병변여녀성년령적관계。방법：2013년45430례이혼부녀재천진금역의학검험중심진행료궁경침윤암사사。수선진행TCT검측,연후대TCT검측결과양성병례행HC2HPV-DNA검측,량항결과위양성자,행음도경급궁경활검。대검측결과안조년령분조진행통계분석。결과：45430례중,AS-CUS급이상자공2234례(4．92%),이30~39세조、40~49세조급50~59세조적발병솔교고。2234례중HC2HPV-DNA양성자1572례(70．37%)。20~29세조HPV감염솔최고,점해년령단ASCUS급이상자총인수적83．52%。궁경침윤암급암전병변발병솔분별위0．16%급1．55%,기중40~49세조급50~59세조궁경침윤암발병솔최고,균위0．28%,원고우기타년령조,차이유통계학의의( P<0．05)。30~39세조급40~49세조적암전병변발병솔분별시1．86%화1．82%,원고우기타년령조,차이유통계학의의( P<0．05)。여궁경침윤암고발년령상비,암전병변고발년령명현제전。결론：천진시이혼부녀적암전병변적고발년령위30~49세,이궁경침윤암적고발년령위40~59세。
Objective: To explore the relationship between invasive carcinoma of cervix, precancerous lesions and the age of married women. Methods:45 430 cases of married women were screened for invasive carcinoma of cervix in the Center of Tianjin KingMed Diagnostics in 2013. The screening method was described as follows:HC2HPV-DNA test was conducted for the TCT positive cases. If both were positive, the colposcopy and cervical biopsy tests were examined. The screening results were statistically analyzed according to age of women. Results: In 45 430 married women, 2 234 cases (4. 92%) were diagnosed as the ASCUS and ASCUS above in TCT test, and the incidence was relatively higher in 30-39 years, 40 -49 years and 50 -59 years old groups. Among the 2 234 cases, 1 572 cases ( 70. 37%) were detected HC2HPV-DNA positive. The HPV infection ratio was the highest in 20-29 years old group which accounted for 83. 52%of the total population of ASCUS and ASCUS above in TCT test in the same age group. The incidence of invasive carcinoma of cervix and precancerous lesions were 0. 16% and 1. 55%, respectively . 40-49 and 50-59 years old groups got the highest incidence(0. 28%) of invasive carcinoma of cervix comparing with the other groups with significant difference(P<0. 05). The 30-39 (1. 86%) and 40 -49 (1. 82%) years old groups had the highest incidence of precancerous lesion comparing with the other groups with significant difference(P<0. 05). The paroxysmal age of precancerous lesion was ob-viously earlier than that of invasive carcinoma of cervix. Conclusion:The paroxysmal age for cervical precancerous lesions was 30~49 years old, while for the invasive carcinoma of cervix was 40~59 years old in married women in Tianjin City.
