食品与药品
食品與藥品
식품여약품
FOOD AND DRUG
2015年
1期
1-4
,共4页
孟照永%王如梅%赵新%韩正%王仲妮
孟照永%王如梅%趙新%韓正%王仲妮
맹조영%왕여매%조신%한정%왕중니
维生素C%反相微乳液%红外光谱
維生素C%反相微乳液%紅外光譜
유생소C%반상미유액%홍외광보
Vitamin C%reverse microemulsion%FT-IR
目的：分别构筑以乙酸异戊酯、肉豆蔻酸异丙酯、葵花籽油和蓖麻油为连续相的包载维生素C（Vit C）微乳液，并研究其红外光谱（IR）性质。方法采取水稀释法构筑三元相图，研究非离子表面活性剂油烯基聚氧乙烯（10）醚（Brij97）水溶液在乙酸异戊酯、肉豆蔻酸异丙酯、葵花籽油、蓖麻油4种不同油相中的相行为；以Brij97、不同油相与Vit C形成反相微乳液，根据Vit C增溶前后IR图谱变化，并通过对羟基伸缩振动峰进行高斯曲线拟合，分析体系微环境的变化。结果 Brij 97分别在4个不同结构的油相体系中形成了反相微乳液。IR光谱分析表明，Vit C增溶后O-H伸缩振动峰在高频区增加了第4个高斯峰，在葵花籽油和蓖麻油体系中，4号新峰的位置随体系油含量的降低，向低频区位移；而在乙酸异戊酯和肉豆蔻酸异丙酯体系中，随体系油含量变化无规律波动。结论乙酸异戊酯和肉豆蔻酸异丙酯为连续相的微乳液形成效率高于葵花籽油和蓖麻油体系；IR分析表明Vit C被完全增溶于反相微乳液的亲水内核中；高斯分峰拟合表明Vit C的引入导致体系微环境增加了一种结合水。
目的：分彆構築以乙痠異戊酯、肉豆蔻痠異丙酯、葵花籽油和蓖痳油為連續相的包載維生素C（Vit C）微乳液，併研究其紅外光譜（IR）性質。方法採取水稀釋法構築三元相圖，研究非離子錶麵活性劑油烯基聚氧乙烯（10）醚（Brij97）水溶液在乙痠異戊酯、肉豆蔻痠異丙酯、葵花籽油、蓖痳油4種不同油相中的相行為；以Brij97、不同油相與Vit C形成反相微乳液，根據Vit C增溶前後IR圖譜變化，併通過對羥基伸縮振動峰進行高斯麯線擬閤，分析體繫微環境的變化。結果 Brij 97分彆在4箇不同結構的油相體繫中形成瞭反相微乳液。IR光譜分析錶明，Vit C增溶後O-H伸縮振動峰在高頻區增加瞭第4箇高斯峰，在葵花籽油和蓖痳油體繫中，4號新峰的位置隨體繫油含量的降低，嚮低頻區位移；而在乙痠異戊酯和肉豆蔻痠異丙酯體繫中，隨體繫油含量變化無規律波動。結論乙痠異戊酯和肉豆蔻痠異丙酯為連續相的微乳液形成效率高于葵花籽油和蓖痳油體繫；IR分析錶明Vit C被完全增溶于反相微乳液的親水內覈中；高斯分峰擬閤錶明Vit C的引入導緻體繫微環境增加瞭一種結閤水。
목적：분별구축이을산이무지、육두구산이병지、규화자유화비마유위련속상적포재유생소C（Vit C）미유액，병연구기홍외광보（IR）성질。방법채취수희석법구축삼원상도，연구비리자표면활성제유희기취양을희（10）미（Brij97）수용액재을산이무지、육두구산이병지、규화자유、비마유4충불동유상중적상행위；이Brij97、불동유상여Vit C형성반상미유액，근거Vit C증용전후IR도보변화，병통과대간기신축진동봉진행고사곡선의합，분석체계미배경적변화。결과 Brij 97분별재4개불동결구적유상체계중형성료반상미유액。IR광보분석표명，Vit C증용후O-H신축진동봉재고빈구증가료제4개고사봉，재규화자유화비마유체계중，4호신봉적위치수체계유함량적강저，향저빈구위이；이재을산이무지화육두구산이병지체계중，수체계유함량변화무규률파동。결론을산이무지화육두구산이병지위련속상적미유액형성효솔고우규화자유화비마유체계；IR분석표명Vit C피완전증용우반상미유액적친수내핵중；고사분봉의합표명Vit C적인입도치체계미배경증가료일충결합수。
Objective To construct Vitamin C (Vit C) encapsulated microemulsions by employing isoamyl acetate, isopropyl myristate, sunflower oil or castor oil as the continuous phase and analyze their infrared spectral (IR) properties. Methods The ternary phase diagrams were constructed by water-dilution method to determine the phase behaviors of aqueous solution of nonionic surfactant polyoxyethylene (10) oleyl ether (Brij97) in isoamyl acetate, isopropyl myristate, sunflower oil and castor oil;the reverse emulsions were formed with Brij97, oil phase and Vit C, and the structural difference of the microemulsion systems with or without Vit C was investigated through FT-IR;the O-H stretching vibration peak and micro-environment of each microemulsion system were analyzed using Gaussian curve fitting method. Results Reverse microemulsions have been formed with Brij97 aqueous solution in four oils respectively. FT-IR measurements and analyses indicated after solubilization of Vit C, the fourth new Gaussian peak in high frequency zone is obtained for the O-H stretching vibration of the microemulsion. The new peak waved irregularly along with changes of oil concentration in the isoamyl acetate and isopropyl myristate systems, while moved to lower frequency region along with the decrease of oil content for the sunflower oil and castor oil systems. Conclusion It is more effective in forming reverse microemulsion with isoamyl acetate and isopropyl myristate as continuous phase than with sunflower oil or castor oil as continuous phase. In addition, FR-IR spectra showed that Vit C was completely wrapped into the hydrophilic kernel of reverse microemulsion, and the multipeak fitting results showed that the introduction of Vit C resulted in a new combined water in the microenvironment of the system.
