CAJ | 학술논문

目的：该研究拟对目前中国医院检验科干化学检验项目的参考区间与对应湿化学的参考区间进行比较，了解医院检验科干、湿化学检验项目参考区间的差异。方法采用基于 Web方式的室间质量评价（EQA）软件系统，收集参加2014年全国干化学和常规化学（湿化学）参考区间调查的实验室所上报的数据，利用配对t检验和中位数 Yates’卡方检验进行统计分析，以确定在同一医疗机构内干化学和湿化学项目的参考区间，以及上下限的中位数之间是否存在差异。结果231家临床实验室回报了23项干、湿化学检验项目。其中69.6％（32／46）的干、湿化学检验项目参考区间上下限配对比较结果差异存在统计学显著性意义。80.4％（37／46）的干、湿化学检验项目参考区间上下限中位数存在位置与分布的显著性统计学差异。结论目前中国同一医疗机构干化学与湿化学检验项目参考区间存在一定差异，参考区间上下限的分布和中位数的位置不同，建议建立中国人群干化学检验项目的参考区间。
목적：해연구의대목전중국의원검험과간화학검험항목적삼고구간여대응습화학적삼고구간진행비교，료해의원검험과간、습화학검험항목삼고구간적차이。방법채용기우 Web방식적실간질량평개（EQA）연건계통，수집삼가2014년전국간화학화상규화학（습화학）삼고구간조사적실험실소상보적수거，이용배대t검험화중위수 Yates’잡방검험진행통계분석，이학정재동일의료궤구내간화학화습화학항목적삼고구간，이급상하한적중위수지간시부존재차이。결과231가림상실험실회보료23항간、습화학검험항목。기중69.6％（32／46）적간、습화학검험항목삼고구간상하한배대비교결과차이존재통계학현저성의의。80.4％（37／46）적간、습화학검험항목삼고구간상하한중위수존재위치여분포적현저성통계학차이。결론목전중국동일의료궤구간화학여습화학검험항목삼고구간존재일정차이，삼고구간상하한적분포화중위수적위치불동，건의건립중국인군간화학검험항목적삼고구간。
Objective To compare the current application status of reference intervals in dry chemistry to the reference inter-vals of anlytes of wet chemistry in the same hospital.Methods By using web-based external quality assessment (EQA) software system,collecting the submitted data from the laboratories which attended national reference intervals investigation of reference intervals of analytes in dry chemistry and wet chemistry,using professional statistical software for analyzing the data,including paired-samples t test and Yates’Chi-square test.Results 231 laboratories submitted their investigation re-sults including the reference intervals of 23 analytes of dry and wet chemistry.69.6% (32/46)of reference intervals of ana-lytes in dry chemistry have significant statistical differences compared with the wet chemistry in paired-samples t tests. 80.4% (37/46)of medians of reference intervals of analytes in dry chemistry had significant statistical differences in loca-tions and distributions compared with medians of reference intervals of wet chemistry in the same institute.Conclusion The reference intervals of analytes of dry chemistry have differences compared with the wet chemistry in the same hospital.The medians of reference interval’s lower and higher limits of dry and wet chemistry have difference in locations and distribu-tions.Proposed to create our own reference intervals of dry chemistry in China.