CAJ | 학술논문

目的：探讨运动训练期间不同时间常压吸氧对小白鼠血清超氧化物歧化酶（SOD）、丙二醛（MDA）含量的影响。方法100只昆明种小白鼠，随机分为非运动训练组、运动训练不吸氧组、运动训练前吸氧组、运动训练后吸氧组、运动训练前后均吸氧组共五组，每组20只。除非运动训练组外，其余各组每天进行30 min 的无负重游泳训练，在运动训练前、后不同时间给予吸入一定量的氧气或不吸氧。运动训练后第21 d 清晨，每组各取10只，测血清 SOD、MDA 含量；另外10只进行游泳力竭运动，运动后取血，测量血清 SOD、MDA。结果在安静状态下运动训练后的各组血清 SOD 活力均高于非运动训练组（P ＜0．05或 P ＜0．01），运动训练不吸氧组和运动训练前吸氧组 SOD 活力低于运动训练后吸氧组（P ＜0．01）；经运动训练不吸氧组和运动训练后吸氧组，其血清 MDA 含量高于非运动训练组和运动训练前吸氧组（P ＜0．05或 P ＜0．01）。力竭运动后，经过运动训练之后不管吸氧与否，其血清 SOD 活力均高于非运动训练组和运动训练前吸氧组（P ＜0．05或 P ＜0．01）；运动训练前吸氧组的 MDA 含量低于运动训练不吸氧组或运动训练后吸氧组（P ＜0．05或 P ＜0．01）。除运动训练后吸氧组外，非运动训练组的 MDA 含量均高于其他各组（P ＜0．05或 P ＜0．01）。结论运动训练期间，于运动训练前吸入一定量的氧气，可减轻自由基的损伤，延缓运动性疲劳的发生，但运动训练后吸氧可能会引起自由基损伤。
목적：탐토운동훈련기간불동시간상압흡양대소백서혈청초양화물기화매（SOD）、병이철（MDA）함량적영향。방법100지곤명충소백서，수궤분위비운동훈련조、운동훈련불흡양조、운동훈련전흡양조、운동훈련후흡양조、운동훈련전후균흡양조공오조，매조20지。제비운동훈련조외，기여각조매천진행30 min 적무부중유영훈련，재운동훈련전、후불동시간급여흡입일정량적양기혹불흡양。운동훈련후제21 d 청신，매조각취10지，측혈청 SOD、MDA 함량；령외10지진행유영력갈운동，운동후취혈，측량혈청 SOD、MDA。결과재안정상태하운동훈련후적각조혈청 SOD 활력균고우비운동훈련조（P ＜0．05혹 P ＜0．01），운동훈련불흡양조화운동훈련전흡양조 SOD 활력저우운동훈련후흡양조（P ＜0．01）；경운동훈련불흡양조화운동훈련후흡양조，기혈청 MDA 함량고우비운동훈련조화운동훈련전흡양조（P ＜0．05혹 P ＜0．01）。력갈운동후，경과운동훈련지후불관흡양여부，기혈청 SOD 활력균고우비운동훈련조화운동훈련전흡양조（P ＜0．05혹 P ＜0．01）；운동훈련전흡양조적 MDA 함량저우운동훈련불흡양조혹운동훈련후흡양조（P ＜0．05혹 P ＜0．01）。제운동훈련후흡양조외，비운동훈련조적 MDA 함량균고우기타각조（P ＜0．05혹 P ＜0．01）。결론운동훈련기간，우운동훈련전흡입일정량적양기，가감경자유기적손상，연완운동성피로적발생，단운동훈련후흡양가능회인기자유기손상。
Objective To observe the effect of inhaling oxygen at different time during sport training on serum superoxide dismutase(SOD)and malomalondialdehyde (MDA)in mice. Methods One hundred Kun-ming mice were randomly divided into five groups:no sport training group,sport training without oxygen in-halation group,oxygen inhalation before sport training group,oxygen inhalation after sport training group,oxy-gen inhalation before and after sport training group.Except for the no sport training group,four groups were forced to swim 30 minutes every day without weight loading,and were or not exposed to 50% oxygen before or/and after exercise training.After 20 days of training,serum MDA and SOD were measured in 50 mice (10 in each group)in a quiet state ,another 10 mice in each group were measured after swimming exhaustion. Re-sults In a quiet state,the SOD activities in every sport training group were higher than the no sport training group(P <0.05 or P <0.01),and SOD activity in sport training without oxygen inhalation group and oxygen inhalation before sport training group were lower than that in oxygen inhalation after sport training group(P <0.01).The MDA amount in sport training without inhalation oxygen group and inhalation oxygen after sport training group were higher than those in no sport training group or inhalation oxygen before sport training group(P <0.05 or P <0.01).After exhaustive exercise,whether inhaling oxygen or not,serum SOD activity of sport training group were higher than no sport training or inhaling oxygen before exercise (P <0.05 or P <0.01);MDA content of oxygen inhalation before sport training was lower than only training without inhalation oxygen,or oxygen inhalation after sport training(P <0.05 or P <0.01).Except for oxygen inhalation after sport training group,the MDA amount of no sport training group were higher than other groups (P <0.05 or P <0.01). Conclusion During sport training,a certain amount of oxygen inhalation before athletic training can help reduce free radical damage,delay the occurrence of sport fatigue,but inhaling oxygen after exercise training may cause free radical damage.