CAJ | 학술논문

目的：探讨应用简易自制新装置进行大鼠断尾采血的效果,建立一种安全、实用、可重复的大鼠采血方法。方法用塑料瓶、木板等制作简易方便的装置固定大鼠,对鼠尾清洗、水浴等合适处理后进行断尾采血。结果自制固定器制作简单、操作方便,1 d可对20只大鼠重复采血6次,出血量0.5~1.0 mL,无大鼠死亡及操作人员受伤等情况发生。结论应用自制大鼠固定装置大鼠采血,血量多、安全性好,是一种理想的大鼠断尾采血新装置。
목적：탐토응용간역자제신장치진행대서단미채혈적효과,건립일충안전、실용、가중복적대서채혈방법。방법용소료병、목판등제작간역방편적장치고정대서,대서미청세、수욕등합괄처리후진행단미채혈。결과자제고정기제작간단、조작방편,1 d가대20지대서중복채혈6차,출혈량0.5~1.0 mL,무대서사망급조작인원수상등정황발생。결론응용자제대서고정장치대서채혈,혈량다、안전성호,시일충이상적대서단미채혈신장치。
Objective To explore the effects of a new simple device for blood collection by tail snipping in rats so as to provide a safe, practical and repeatable method. Methods The rats were held by simple devices which made from plastic bottles and block and treated by some moderate ways for blood collection. Results The device was easy to be made and handled. 20 rats could have 6 times of blood collec-tion by this device in one day. There was no mouse death and no person injure during the experimental course. Conclusion This device is a safe and ideal equipment for blood collection by tail snipping in rats.