CAJ | 학술논문

目的：观察虫卵经氰氨化钙合成药物作用后的形态改变，为进一步研究氰氨化钙合成药物杀灭血吸虫虫卵作用机理提供依据。方法向含有血吸虫虫卵的阳性牛粪中加入氰氨化钙合成药物并搅拌，模拟野粪自然形态堆放于洲滩上；同时设空白对照。于1、2、3、7d后分别取样，收集血吸虫虫卵，于显微镜下观察虫卵形态。结果虫卵经氰氨化钙合成药物作用后，颜色逐步加深，毛蚴萎缩，卵壳变厚，3d后胚膜不完整，7d后毛蚴严重变形；对照组毛蚴未见明显萎缩。结论氰氨化钙合成药物对虫卵胚膜及毛蚴有损伤作用，且随时间延长而损伤加重。
목적：관찰충란경청안화개합성약물작용후적형태개변，위진일보연구청안화개합성약물살멸혈흡충충란작용궤리제공의거。방법향함유혈흡충충란적양성우분중가입청안화개합성약물병교반，모의야분자연형태퇴방우주탄상；동시설공백대조。우1、2、3、7d후분별취양，수집혈흡충충란，우현미경하관찰충란형태。결과충란경청안화개합성약물작용후，안색축보가심，모유위축，란각변후，3d후배막불완정，7d후모유엄중변형；대조조모유미견명현위축。결론청안화개합성약물대충란배막급모유유손상작용，차수시간연장이손상가중。
Objective To study the morphological change of Schistosoma japonicum eggs processed by calcium cyanamide synthetic drug,so as to provide the basis for further study of the mechanism that calcium cyanamide synthetic drug to schisto?some eggs. Methods The calcium cyanamide synthetic drug was added to the cattle feces containing schistosome eggs and mixed up,and then the cattle feces was stacked as original shape on the marshland. Blank controls were set at the same time. The cattle feces samples were collected and the schistosome eggs were observed under a microscope on the 1st,2nd,3rd,7th day after the experiment. Results By the effect of calcium cyanamide synthetic drug,the color of eggs was deepening gradual?ly,the miracidia were atrophied,and the shells of eggs were thickened. The embryonic membrane of miracidia was no longer completed 3 days later,and the miracidia were deformed severely 7 days later. The atrophy of miracidia was not obvious in the blank controls. Conclusion The schistosome miracidia and embryonic membrane can be damaged by the calcium cyanamide synthetic drug,and worse damaged with time extending.