CAJ | 학술논문

目的：提高晚期血吸虫病（晚血）合并HBV感染患者抗病毒治疗的疗效，减少并发症，提高生活质量。方法选择2003年2月至2012年12月在作者所在医院行抗病毒治疗的27例腹水型晚血合并HBV感染患者作为治疗组，对其抗HBV治疗的临床及随访资料进行回顾性分析；同时以31例未作抗乙肝病毒治疗、病情基本相同的腹水型晚血合并HBV感染患者作为对照。结果治疗组自发性腹膜炎、肝性脑病、肝肾综合征、上消化道出血、原发性肝癌的发生率明显低于对照组，肝功能、肾功能、凝血酶原时间检测指标明显优于对照组，死亡率明显低于对照组。结论腹水型晚期血吸虫病合并HBV感染患者通过抗病毒治疗，可明显改善患者愈后，提高患者生存率。
목적：제고만기혈흡충병（만혈）합병HBV감염환자항병독치료적료효，감소병발증，제고생활질량。방법선택2003년2월지2012년12월재작자소재의원행항병독치료적27례복수형만혈합병HBV감염환자작위치료조，대기항HBV치료적림상급수방자료진행회고성분석；동시이31례미작항을간병독치료、병정기본상동적복수형만혈합병HBV감염환자작위대조。결과치료조자발성복막염、간성뇌병、간신종합정、상소화도출혈、원발성간암적발생솔명현저우대조조，간공능、신공능、응혈매원시간검측지표명현우우대조조，사망솔명현저우대조조。결론복수형만기혈흡충병합병HBV감염환자통과항병독치료，가명현개선환자유후，제고환자생존솔。
Objective To improve the curative effect of advanced schistosomiasis patients with ascites and HBV infection. Methods A total of 27 advanced schistosomiasis patients with ascites and HBV infection were selected as a trial group and giv?en with anti?HBV treatment and 31 corresponding patients were as the controls and did not received anti?HBV treatment from February 2003 to December 2012. Results The incidence of ascites recurrence spontaneous peritonitis hepatic encephalopa?thy hepatorenal syndrome upper gastrointestinal bleeding and primary liver cancer in the trial group were significantly lower than those in the control group. The detection indexes of liver function renal function and prothrombin time in the trial group were superior to those in the control group. The mortality in the treatment group was also significantly lower than that in the con?trol group. Conclusion The anti?HBV treatment in the advanced schistosomiasis patients with ascites and HBV infection can obviously improve their physical conditions the survival rate and their life qualities.