CAJ | 학술논문

目的：探讨尿毒症患者血液透析（ HD）前后左心室Tei指数的变化幅度及其与发生心血管事件的相关性。方法应用超声检测因心血管事件住院的83例尿毒症患者（观察组）及无心血管事件的90例尿毒症患者（对照组）透析前后左心室射血分数（ EF）、左心室缩短分数（ FS）、二尖瓣舒张早期与舒张晚期血流峰值之比（ E／A）、左心室Tei指数，并计算EF、FS、E／A比值、Tei指数在血液透析前后的变化幅度；采用自身对照，t检验。结果血液透析前后观察组、对照组EF、FS、E／A比值、Tei指数差异均有统计学意义（ P＜0.05）；EF、FS、E／A比值的变化幅度两组间差异无统计学意义（ P＞0.05），Tei指数变化幅度差异有统计学意义（ P＜0.05）。结论尿毒症患者血液透析后左心室Tei指数升高程度与发生心血管事件的风险度密切相关。借助Tei指数的变化可预测、预防尿毒症患者心血管事件的发生。
목적：탐토뇨독증환자혈액투석（ HD）전후좌심실Tei지수적변화폭도급기여발생심혈관사건적상관성。방법응용초성검측인심혈관사건주원적83례뇨독증환자（관찰조）급무심혈관사건적90례뇨독증환자（대조조）투석전후좌심실사혈분수（ EF）、좌심실축단분수（ FS）、이첨판서장조기여서장만기혈류봉치지비（ E／A）、좌심실Tei지수，병계산EF、FS、E／A비치、Tei지수재혈액투석전후적변화폭도；채용자신대조，t검험。결과혈액투석전후관찰조、대조조EF、FS、E／A비치、Tei지수차이균유통계학의의（ P＜0.05）；EF、FS、E／A비치적변화폭도량조간차이무통계학의의（ P＞0.05），Tei지수변화폭도차이유통계학의의（ P＜0.05）。결론뇨독증환자혈액투석후좌심실Tei지수승고정도여발생심혈관사건적풍험도밀절상관。차조Tei지수적변화가예측、예방뇨독증환자심혈관사건적발생。
Objective To explore the rangeability of left ventricular Tei index in uremic patient before and after hemodialysis ( HD) and its association with cardiovascular events .Methods Ultrasound was performed on 83 hospitalized uremic patients owing to cardiovascular events ( observation group ) and 90 uremic patients without cardiovascular events ( control group ) .The left ventricular ejection fraction ( EF ) , fractional shortening(FS),E/A ratio and left ventricular Tei index before and after HD were measured ,and then calculated the range of them .Statistical analysis was performed with the t test by self-control method . Results The differences of EF , FS, E/A and left ventricular Tei index between before and after HD had statistical significant ( P<0.05 ) .The range of these indexes had no statistical significant betwwen the two groups ( P>0.05 ) except for the left ventricular Tei index ( P<0.05 ) .Conclusions The increasing range of the left ventricular Tei index of uremic patient after HD is closely related to cardiovascular events .The change of Tei index can forecast and prevent the cardiovascular events .