CAJ | 학술논문

目的：运用文献计量学的方法探讨2003—2013年国内外转化医学的发展现状、国家间合作、学科分布以及研究热点等特点，为相关研究提供参考。方法计算机检索PubMed、Web of Science、万方数据知识服务平台、中文科技期刊数据库、中国知网期刊全文数据库和中国生物医学文献数据库，查找国内外关于转化医学研究的文献，检索时间均限定为2003年1月1日—2013年12月31日。运用Excel 2013提取文献的基本信息，社会网络分析软件Ucinet 6．0分析国家间的合作关系，HistCite 12．03进行文献时间序列分析。结果共纳入中外文转化医学研究文献4143篇。通过对文献的国家分布及其合作情况进行分析，显示开展转化医学研究的63个国家主要集中在欧洲和北美地区，其中美国的发文量、文献的被引用频次以及与其他国家的合作度最高。从文献的期刊和学科分布来看，国外发表转化医学相关期刊的种类比国内多（711比314），刊均载文量也比国内多（4．5比2．8）。国内外转化医学研究热点主要集中在基础实验和肿瘤方面，此外国内还特别关注了中医药的转化研究。引文时间序列分析显示与转化医学研究发展相关的重要文献有50篇，主要集中在2003—2011年。结论转化医学研究是当前医学研究中的热点，欧洲和北美国家处于主导地位。国内转化医学研究水平与国外差距较大，主要体现在文献的数量、被引用情况以及与其他国家的合作度均较低。
목적：운용문헌계량학적방법탐토2003—2013년국내외전화의학적발전현상、국가간합작、학과분포이급연구열점등특점，위상관연구제공삼고。방법계산궤검색PubMed、Web of Science、만방수거지식복무평태、중문과기기간수거고、중국지망기간전문수거고화중국생물의학문헌수거고，사조국내외관우전화의학연구적문헌，검색시간균한정위2003년1월1일—2013년12월31일。운용Excel 2013제취문헌적기본신식，사회망락분석연건Ucinet 6．0분석국가간적합작관계，HistCite 12．03진행문헌시간서렬분석。결과공납입중외문전화의학연구문헌4143편。통과대문헌적국가분포급기합작정황진행분석，현시개전전화의학연구적63개국가주요집중재구주화북미지구，기중미국적발문량、문헌적피인용빈차이급여기타국가적합작도최고。종문헌적기간화학과분포래간，국외발표전화의학상관기간적충류비국내다（711비314），간균재문량야비국내다（4．5비2．8）。국내외전화의학연구열점주요집중재기출실험화종류방면，차외국내환특별관주료중의약적전화연구。인문시간서렬분석현시여전화의학연구발전상관적중요문헌유50편，주요집중재2003—2011년。결론전화의학연구시당전의학연구중적열점，구주화북미국가처우주도지위。국내전화의학연구수평여국외차거교대，주요체현재문헌적수량、피인용정황이급여기타국가적합작도균교저。
Objective Bibliometrics was used to compare the exploration difference of develop-ment status, collaboration of different countries , distribution of subjects and research highlights in translational medicine literatures from 2003 to 2013, provide a reference for related research .Methods We systematically searched PubMed, Web of science, Wanfang, VIP, CNKI and CBM database to collect translational medicine literatures from Jan .1 2003 to Dec .31 2013 .Excel 2013 was used to extract the basic information , Ucinet 6.0 was used to analyze the collaborations among countries , and HistCite 12.03 was used to conduct time series analysis .Results A total of 4 143 articles from 63 countries were retrieved .Most of the articles came from European and North America , among which America was the No 1 in publishing translational articles , citation times, and collaborating with other countries .As to the distribution of journals and subjects of translational medicine litera-tures , we could find that the number of international journals publishing translational medicine litera -tures were more than domestic journals (711 vs.314), as well as the average number of transla-tional literatures published in each journal ( 4.5 vs.2.8 ) .The research highlights of international literatures concentrated on basic experiments and cancer researches , and the domestic literatures concentrated on the above areas but also focused on the translation of traditional Chinese medicine . The results of time series analysis indicated that there were 50 articles mainly published from 2003 to 2011, which was important to the development of translational medicine .Conclusion Translational medicine was a hot point in medical research , which was led by European and North America coun-tries.The research level of translational medicine in our country was lower than international coun -tries, for the fewer published articles , citation times and collaborations with other countries .