中华现代护理杂志
中華現代護理雜誌
중화현대호리잡지
CHINESE JOURNAL OF MODERN NURSING
2015年
6期
697-699,700
,共4页
妊娠,异位%甲氨蝶呤%米非司酮%护理
妊娠,異位%甲氨蝶呤%米非司酮%護理
임신,이위%갑안접령%미비사동%호리
Ectopic gestation%Methotrexate%Mifepristone%Nursing care
目的：探讨甲氨蝶呤联合米非司酮治疗异位妊娠的临床护理措施。方法对128例异位妊娠患者行甲氨蝶呤联合米非司酮药物保守治疗，测定患者血β-人绒毛膜促性腺激素（HCG）水平，B超检查妊娠包块大小，用药过程中给予心理、饮食和日常活动、病情观察、药物不良反应等综合护理，并对患者进行出院指导。结果128例患者中，121例治疗成功，成功率为94．5％。治疗后1周与治疗前相比，患者血β-HCG水平和异位妊娠包块直径均下降，差异有统计学意义（ t值分别为33．2，8．9；P ＜0．05）；治疗后2，3，4周，患者血β-HCG水平低于治疗后1周，差异有统计学意义（t值分别为64．2，78．3，105．9；P＜0．05）；治疗后2，3，4周，患者包块直径小于治疗后1周，差异有统计学意义（t值分别为6．4，7．5，8．3；P＜0．05）。治疗过程中有5例（3．9％）患者出现胃肠道反应，分别有3例（2．3％）患者转氨酶轻度升高与白细胞减少，分别有2例（1．6％）患者出现口腔溃疡与骨髓抑制，给予相应处理后均恢复正常。结论甲氨蝶呤联合米非司酮保守治疗异位妊娠时，应给予患者积极的心理护理，加强临床护理，密切观察患者病情变化，以促进患者康复。
目的：探討甲氨蝶呤聯閤米非司酮治療異位妊娠的臨床護理措施。方法對128例異位妊娠患者行甲氨蝶呤聯閤米非司酮藥物保守治療，測定患者血β-人絨毛膜促性腺激素（HCG）水平，B超檢查妊娠包塊大小，用藥過程中給予心理、飲食和日常活動、病情觀察、藥物不良反應等綜閤護理，併對患者進行齣院指導。結果128例患者中，121例治療成功，成功率為94．5％。治療後1週與治療前相比，患者血β-HCG水平和異位妊娠包塊直徑均下降，差異有統計學意義（ t值分彆為33．2，8．9；P ＜0．05）；治療後2，3，4週，患者血β-HCG水平低于治療後1週，差異有統計學意義（t值分彆為64．2，78．3，105．9；P＜0．05）；治療後2，3，4週，患者包塊直徑小于治療後1週，差異有統計學意義（t值分彆為6．4，7．5，8．3；P＜0．05）。治療過程中有5例（3．9％）患者齣現胃腸道反應，分彆有3例（2．3％）患者轉氨酶輕度升高與白細胞減少，分彆有2例（1．6％）患者齣現口腔潰瘍與骨髓抑製，給予相應處理後均恢複正常。結論甲氨蝶呤聯閤米非司酮保守治療異位妊娠時，應給予患者積極的心理護理，加彊臨床護理，密切觀察患者病情變化，以促進患者康複。
목적：탐토갑안접령연합미비사동치료이위임신적림상호리조시。방법대128례이위임신환자행갑안접령연합미비사동약물보수치료，측정환자혈β-인융모막촉성선격소（HCG）수평，B초검사임신포괴대소，용약과정중급여심리、음식화일상활동、병정관찰、약물불량반응등종합호리，병대환자진행출원지도。결과128례환자중，121례치료성공，성공솔위94．5％。치료후1주여치료전상비，환자혈β-HCG수평화이위임신포괴직경균하강，차이유통계학의의（ t치분별위33．2，8．9；P ＜0．05）；치료후2，3，4주，환자혈β-HCG수평저우치료후1주，차이유통계학의의（t치분별위64．2，78．3，105．9；P＜0．05）；치료후2，3，4주，환자포괴직경소우치료후1주，차이유통계학의의（t치분별위6．4，7．5，8．3；P＜0．05）。치료과정중유5례（3．9％）환자출현위장도반응，분별유3례（2．3％）환자전안매경도승고여백세포감소，분별유2례（1．6％）환자출현구강궤양여골수억제，급여상응처리후균회복정상。결론갑안접령연합미비사동보수치료이위임신시，응급여환자적겁적심리호리，가강림상호리，밀절관찰환자병정변화，이촉진환자강복。
Objective To explore the clinical nursing of Methotrexate combined with Mifepristone in patients with ectopic gestation .Methods Totals of 128 patients with ectopic gestation were treated by Methotrexate combined with Mifepristone , and blood β-HCG level and lump diameter size were measured .The patients were given comprehensive nursing including psychology , diet and daily activities , disease observation , drug adverse reaction and discharge guidance .Results The rate of successful treatment was 94.5%(121/128).The level of blood β-HCG and diameter of lump after 1 week were significantly smaller than those before the treatment (t=33.2,8.9, respectively;P<0.05).The level of blood β-HCG after 2,3,4 weeks were significantly lower than those after 1 week (t=64.2,78.3,105.9, respectively;P<0.05).And the diameter of lump after 2,3,4 weeks were significantly smaller than those after 1 week (t=6.4,7.5,8.3, respectively;P<0.05).Five patients (3.9%) had gastrointestinal reaction, three patients (2.3%) had slightly elevation of transaminase and leucopenia , two patients ( 1.6%) had oral ulcer and bone marrow suppression .Those symptoms were disappeared after treatment .Conclusions During the treatment of ectopic pregnancy , patients should be given positive psychological care , close clinical nursing and disease observation to promote the rehabilitation of patients .
