中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
6期
23-24
,共2页
奥美拉唑%胃食管反流病%临床研究
奧美拉唑%胃食管反流病%臨床研究
오미랍서%위식관반류병%림상연구
Omeprazole%Gastroesophageal reflux disease%Clinical research
目的：探讨奥美拉唑治疗胃食管反流病(GERD)的临床疗效。方法：2013年9月-2014年6月收治GERD患者60例，随机分成对照组和观察组，各30例，观察组服用奥美拉唑肠溶片20 mg/次，2次/d；对照组服用雷尼替丁150 mg/次，2次/d。治疗8周后，观察两组的临床症状积分和内镜分级。结果：观察组治疗后的临床症状积分和内镜分级改善明显优于对照组，总有效率93.33%。结论：奥美拉唑治疗GERD疗效显著，且疗效优于H2受体阻滞剂雷尼替丁。
目的：探討奧美拉唑治療胃食管反流病(GERD)的臨床療效。方法：2013年9月-2014年6月收治GERD患者60例，隨機分成對照組和觀察組，各30例，觀察組服用奧美拉唑腸溶片20 mg/次，2次/d；對照組服用雷尼替丁150 mg/次，2次/d。治療8週後，觀察兩組的臨床癥狀積分和內鏡分級。結果：觀察組治療後的臨床癥狀積分和內鏡分級改善明顯優于對照組，總有效率93.33%。結論：奧美拉唑治療GERD療效顯著，且療效優于H2受體阻滯劑雷尼替丁。
목적：탐토오미랍서치료위식관반류병(GERD)적림상료효。방법：2013년9월-2014년6월수치GERD환자60례，수궤분성대조조화관찰조，각30례，관찰조복용오미랍서장용편20 mg/차，2차/d；대조조복용뢰니체정150 mg/차，2차/d。치료8주후，관찰량조적림상증상적분화내경분급。결과：관찰조치료후적림상증상적분화내경분급개선명현우우대조조，총유효솔93.33%。결론：오미랍서치료GERD료효현저，차료효우우H2수체조체제뢰니체정。
Objective:To investigate the clinical curative effect of omeprazole in the treatment of gastroesophageal reflux disease(GERD).Methods:60 patients with GERD were selected from September 2013 to June 2014.They were randomly divided into the control group and the observation group with 30 cases in each.The observation group were given omeprazole enteric-coated tablets 20 mg/time,2 times/d;the control group were given ranitidine 150 mg/time,2 times/d.After 8 weeks of the treatment,we observed the changes of clinical symptoms score and endoscopic classification of two groups.Results:The changes of clinical symptoms score and endoscopic grading of the observation group were improved significantly better than those of the control group after the treatment.The total efficiency was 93.33%.Conclusion:The clinical curative effect of omeprazole for GERD is significantly.The curative effect is better than the H2 receptor antagonist ranitidine.
