临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
CHINESE JOURNAL OF CLINICAL RATIONAL DRUG USE
2015年
5期
16-17,28
,共3页
氨基末端B型脑钠肽前体%动态测定%急性呼吸窘迫综合征%生存预后
氨基末耑B型腦鈉肽前體%動態測定%急性呼吸窘迫綜閤徵%生存預後
안기말단B형뇌납태전체%동태측정%급성호흡군박종합정%생존예후
N-terminal pro-brain natriu-retic peptid%Dynamic measurement%ARDS%prognosis
目的：评估血浆 NT_proBNp 的动态变化在急性呼吸窘迫综合征（ARDS）患者预后评估价值。方法采用前瞻性观察方法，观察35例急性呼吸窘迫综合征患者的血浆 NT_proBNp 的变化。结果 ROC 曲线分析显示△NT_proBNp3是急性呼吸窘迫综合征患者病死率预测的可靠指标。结论血浆 NT_proBNp 动态测定可能成为急性呼吸窘迫综合征患者预后评估的重要指标。
目的：評估血漿 NT_proBNp 的動態變化在急性呼吸窘迫綜閤徵（ARDS）患者預後評估價值。方法採用前瞻性觀察方法，觀察35例急性呼吸窘迫綜閤徵患者的血漿 NT_proBNp 的變化。結果 ROC 麯線分析顯示△NT_proBNp3是急性呼吸窘迫綜閤徵患者病死率預測的可靠指標。結論血漿 NT_proBNp 動態測定可能成為急性呼吸窘迫綜閤徵患者預後評估的重要指標。
목적：평고혈장 NT_proBNp 적동태변화재급성호흡군박종합정（ARDS）환자예후평고개치。방법채용전첨성관찰방법，관찰35례급성호흡군박종합정환자적혈장 NT_proBNp 적변화。결과 ROC 곡선분석현시△NT_proBNp3시급성호흡군박종합정환자병사솔예측적가고지표。결론혈장 NT_proBNp 동태측정가능성위급성호흡군박종합정환자예후평고적중요지표。
Objective To investigate the prognostic value of dynamic changes of plasmic NT_proBNp concentration in patients with ARDS, Methods A prospective observational study was conducted to collect 35 patients with ARDS,the plasmic NT_proBNp of whom were changed, The NT_proBNp plasma levels of included patients were tested in the time points of day 0, day 1st and day 3rd during their intensive care unit stay, △ NT_proBNp1 and △ NT_proBNp3 were defined as plasmic NT_proBNp difference value of day 1,day 3 with day 0 respectively,meanwhile △ NT_proBNp 3_1 was defined as the plasmic NT_proBNp difference value between day 3rd and day 1st, Hospitalization day 28th mortality were compared between death and sur_vival group, ROC curve of △ NT_proBNp1,△ NT_proBNp3,△ NT_proBNp3_1,NT_proBNp0,NT_proBNp1,NT_proBNp3 and ApACHE Ⅱwere compared to assess the predictive value of mortality in ARDS patients, Results ROC curve analysis showed△ NT_proBNp3 is a reliable indicator of mortality in patients with ARDS, Conclusion plasma NT_proBNp dynamic measure_ment may become a more effective means of consolidation in patients with ARDS prognosis.
