中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
5期
72-73
,共2页
不同剂型%美托洛尔%扩张型心肌病%临床疗效
不同劑型%美託洛爾%擴張型心肌病%臨床療效
불동제형%미탁락이%확장형심기병%림상료효
Different dosage forms%Metoprolol%Dilated cardiomyopathy%Clinical curative effect
目的：探讨应用不同剂型美托洛尔片治疗扩张型心肌病的临床效果。方法：2013年7月-2014年7月收治扩张型心肌病患者100例，对其临床资料进行回顾性分析。按照随机原则将患者分为两组，各50例，均使用美托洛尔治疗。对照组初始使用剂量6.25 mg，观察组初始使用剂量11.875 mg，而后逐渐加倍至靶剂量，对比两组临床效果。结果：观察组治疗总有效率92.0%，对照组66.0%，差异有统计学意义(P＜0.05)。对照组心功能指标改变情况治疗前后对比差异无统计学意义(P＞0.05)，观察组治疗前后对比差异有统计学意义(P＜0.05)，两组治疗后对比差异有统计学意义(P＜0.05)。结论：应用美托洛尔治疗扩张型心肌病临床效果显著，可对心功能予以有效改善，降低临床死亡率，具有推广价值。
目的：探討應用不同劑型美託洛爾片治療擴張型心肌病的臨床效果。方法：2013年7月-2014年7月收治擴張型心肌病患者100例，對其臨床資料進行迴顧性分析。按照隨機原則將患者分為兩組，各50例，均使用美託洛爾治療。對照組初始使用劑量6.25 mg，觀察組初始使用劑量11.875 mg，而後逐漸加倍至靶劑量，對比兩組臨床效果。結果：觀察組治療總有效率92.0%，對照組66.0%，差異有統計學意義(P＜0.05)。對照組心功能指標改變情況治療前後對比差異無統計學意義(P＞0.05)，觀察組治療前後對比差異有統計學意義(P＜0.05)，兩組治療後對比差異有統計學意義(P＜0.05)。結論：應用美託洛爾治療擴張型心肌病臨床效果顯著，可對心功能予以有效改善，降低臨床死亡率，具有推廣價值。
목적：탐토응용불동제형미탁락이편치료확장형심기병적림상효과。방법：2013년7월-2014년7월수치확장형심기병환자100례，대기림상자료진행회고성분석。안조수궤원칙장환자분위량조，각50례，균사용미탁락이치료。대조조초시사용제량6.25 mg，관찰조초시사용제량11.875 mg，이후축점가배지파제량，대비량조림상효과。결과：관찰조치료총유효솔92.0%，대조조66.0%，차이유통계학의의(P＜0.05)。대조조심공능지표개변정황치료전후대비차이무통계학의의(P＞0.05)，관찰조치료전후대비차이유통계학의의(P＜0.05)，량조치료후대비차이유통계학의의(P＜0.05)。결론：응용미탁락이치료확장형심기병림상효과현저，가대심공능여이유효개선，강저림상사망솔，구유추엄개치。
Objective:To explore the clinical effect of applying different dosage forms of metoprolol tablets in the treatment of dilated cardiomyopathy.Methods:100 patients with dilated cardiomyopathy were selected from July 2013 to July 2014.The clinical data were retrospectively analyzed.The patients were divided into two groups with 50 cases in each according to the principle of random.They were treated by metoprolol.The initial dosage of the control group was 6.25 mg.The initial dosage of the observation group was 11.875 mg.Then it gradually doubled to target dose.The clinical effects of two groups were compared.Results:The treatment total effective rate of the observation group was 92.0%;the control group was 66.0%;the difference was statistically significant(P<0.05).The contrast difference of the cardiac function indexes change before and after treatment in the control group was not significant(P>0.05).The contrast difference before and after treatment in the observation group was statistically significant(P<0.05).The contrast difference of two groups after treatment was statistically significant(P<0.05).Conclusion:Application of metoprolol in the treatment of dilated cardiomyopathy has significant clinical effect.It can effectively improve heart function and reduce mortality.It has popularization value.
