中国现代药物应用
中國現代藥物應用
중국현대약물응용
CHINESE JOURNAL OF MODERN DRUG APPLICATION
2015年
5期
8-9,10
,共3页
膀胱副节瘤%手术%病理诊断%鉴别诊断
膀胱副節瘤%手術%病理診斷%鑒彆診斷
방광부절류%수술%병리진단%감별진단
Bladder paragangliomas%Surgery%Pathological diagnosis%Differential diagnosis
目的:探讨膀胱副节瘤临床诊治与病理特点。方法5例膀胱副节瘤患者作为本次的研究对象,并对患者的临床资料进行回顾性分析,观察膀胱副节瘤临床诊治与病理特点。结果5例患者均顺利完成手术,其中术中出血量为61~253 ml。切除肿瘤完整,呈椭圆形或圆形,直径1.6~2.6 cm,表面无明显包膜,切面呈灰白色或者黄褐色。3例术前血压升高,术后血压在3d内降至正常范围。本组5例患者均获得随访,随访时间60个月,其中1例患者术后48个月发生腰椎转移,其余患者均未发生复发现象。结论膀胱副节瘤较为罕见,诊断时应重视临床表现,例如与排尿有关的头晕、头痛等高血压发作症状及肉眼血尿等,同时影像学及实验室检查均有利于对本病进行诊断及鉴别,术前不主张活检,手术为首选治疗手段,术后重视随访。
目的:探討膀胱副節瘤臨床診治與病理特點。方法5例膀胱副節瘤患者作為本次的研究對象,併對患者的臨床資料進行迴顧性分析,觀察膀胱副節瘤臨床診治與病理特點。結果5例患者均順利完成手術,其中術中齣血量為61~253 ml。切除腫瘤完整,呈橢圓形或圓形,直徑1.6~2.6 cm,錶麵無明顯包膜,切麵呈灰白色或者黃褐色。3例術前血壓升高,術後血壓在3d內降至正常範圍。本組5例患者均穫得隨訪,隨訪時間60箇月,其中1例患者術後48箇月髮生腰椎轉移,其餘患者均未髮生複髮現象。結論膀胱副節瘤較為罕見,診斷時應重視臨床錶現,例如與排尿有關的頭暈、頭痛等高血壓髮作癥狀及肉眼血尿等,同時影像學及實驗室檢查均有利于對本病進行診斷及鑒彆,術前不主張活檢,手術為首選治療手段,術後重視隨訪。
목적:탐토방광부절류림상진치여병리특점。방법5례방광부절류환자작위본차적연구대상,병대환자적림상자료진행회고성분석,관찰방광부절류림상진치여병리특점。결과5례환자균순리완성수술,기중술중출혈량위61~253 ml。절제종류완정,정타원형혹원형,직경1.6~2.6 cm,표면무명현포막,절면정회백색혹자황갈색。3례술전혈압승고,술후혈압재3d내강지정상범위。본조5례환자균획득수방,수방시간60개월,기중1례환자술후48개월발생요추전이,기여환자균미발생복발현상。결론방광부절류교위한견,진단시응중시림상표현,례여여배뇨유관적두훈、두통등고혈압발작증상급육안혈뇨등,동시영상학급실험실검사균유리우대본병진행진단급감별,술전불주장활검,수술위수선치료수단,술후중시수방。
Objective To investigate the clinical diagnosis and treatment of bladder paragangliomas and its pathological characteristics. Methods There were 5 patients with bladder paragangliomas as the research subjects of this study. Their clinical data were retrospectively analyzed for observation of clinical diagnosis and treatment and pathological characteristics of bladder paragangliomas. Results All of the 5 patients received successful surgery, and the intraoperative bleeding volume was 61~253 ml. Tumor resection was complete as oval or round in 1.6~2.6 cm of diameter without obvious coated surface, and the incision surface was hoary or tawny. There were 3 cases with elevated blood pressure, which returned to normal range within 3 d. Follow-up was taken on all the 5 cases for 60 months. Among them, there was 1 case with lumbar vertebra metastasis in 48 months af-ter treatment, and the other cases had no relapse. Conclusion Bladder paragangliomas is rare, and its clinical manifestations are important in diagnosis, such as hypertensive symptom of dizziness related with micturition and headache and visible hematuresis. Imageology and laboratory examination are all helpful for diagnosis and iden-tification of the disease. Preoperative biopsy is not advocated. The main treatment method is surgery, and postop-erative follow-up is essential.