中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
5期
11-12
,共2页
婴幼儿%毛细支气管炎%合并细菌感染%菌谱变迁%耐药性
嬰幼兒%毛細支氣管炎%閤併細菌感染%菌譜變遷%耐藥性
영유인%모세지기관염%합병세균감염%균보변천%내약성
Infant%Capillary bronchitis%With bacteria infection%Bacteria spectrum change%Drug resistance
目的：对顺德北滘地区毛细支气管炎合并细菌感染患儿病原菌谱变化以及细菌耐药性进行分析，指导临床合理选择抗生素。方法：2014年1月-2015年3月收治毛细支气管炎合并细菌感染患儿372例，对患儿的痰培养标本进行常规培养与药敏试验。结果：372例痰液标本共分离得到15种133株菌株，以革兰阴性菌为主。革兰阴性菌前3位为大肠埃希菌(25.56%)、流感嗜血杆菌(24.06%)、肺炎克雷伯菌肺炎亚种(21.05%)。其对头孢克洛、头孢呋辛、哌拉西林的耐药程度较高，对阿莫西林克拉维酸钾、头孢西丁、氧氟沙星、头孢他啶及头孢噻肟的耐药程度比较低，对亚胺培南、美罗培南高度敏感。革兰阳性菌为金黄色葡萄球菌(8.27%)、肺炎链球菌(4.51%)，溶血葡萄球菌(1.5%)。其对克林霉素、红霉素、青霉素的耐药程度较高，对氧氟沙星、四环素的耐药程度较低，对万古霉素高度敏感。结论：临床医师应重视病原菌检测及药敏试验结果，谨慎、合理用药，提高疗效，减少耐药菌株产生，减轻患儿痛苦。
目的：對順德北滘地區毛細支氣管炎閤併細菌感染患兒病原菌譜變化以及細菌耐藥性進行分析，指導臨床閤理選擇抗生素。方法：2014年1月-2015年3月收治毛細支氣管炎閤併細菌感染患兒372例，對患兒的痰培養標本進行常規培養與藥敏試驗。結果：372例痰液標本共分離得到15種133株菌株，以革蘭陰性菌為主。革蘭陰性菌前3位為大腸埃希菌(25.56%)、流感嗜血桿菌(24.06%)、肺炎剋雷伯菌肺炎亞種(21.05%)。其對頭孢剋洛、頭孢呋辛、哌拉西林的耐藥程度較高，對阿莫西林剋拉維痠鉀、頭孢西丁、氧氟沙星、頭孢他啶及頭孢噻肟的耐藥程度比較低，對亞胺培南、美囉培南高度敏感。革蘭暘性菌為金黃色葡萄毬菌(8.27%)、肺炎鏈毬菌(4.51%)，溶血葡萄毬菌(1.5%)。其對剋林黴素、紅黴素、青黴素的耐藥程度較高，對氧氟沙星、四環素的耐藥程度較低，對萬古黴素高度敏感。結論：臨床醫師應重視病原菌檢測及藥敏試驗結果，謹慎、閤理用藥，提高療效，減少耐藥菌株產生，減輕患兒痛苦。
목적：대순덕북공지구모세지기관염합병세균감염환인병원균보변화이급세균내약성진행분석，지도림상합리선택항생소。방법：2014년1월-2015년3월수치모세지기관염합병세균감염환인372례，대환인적담배양표본진행상규배양여약민시험。결과：372례담액표본공분리득도15충133주균주，이혁란음성균위주。혁란음성균전3위위대장애희균(25.56%)、류감기혈간균(24.06%)、폐염극뢰백균폐염아충(21.05%)。기대두포극락、두포부신、고랍서림적내약정도교고，대아막서림극랍유산갑、두포서정、양불사성、두포타정급두포새우적내약정도비교저，대아알배남、미라배남고도민감。혁란양성균위금황색포도구균(8.27%)、폐염련구균(4.51%)，용혈포도구균(1.5%)。기대극림매소、홍매소、청매소적내약정도교고，대양불사성、사배소적내약정도교저，대만고매소고도민감。결론：림상의사응중시병원균검측급약민시험결과，근신、합리용약，제고료효，감소내약균주산생，감경환인통고。
Objective:To analyze the pathogenic bacteria spectrum change and bacteria drug resistance of capillary bronchitis children with bacteria infection in Shunde Beijiao area,to guide reasonable choice of antibiotics in clinic.Methods:372 capillary bronchitis children with bacteria infection were selected from January 2014 to March 2015.The sputum culture specimens of children were given conventional culture and drug susceptibility test.Results:15 species of 133 strains were isolated from 372 sputum samples,the gram negative bacterium was mainly.The former three gram negative bacterium were escherichia coli(25.56%),haemophilus influenzae(24.06%),klebsiella pneumonia subspecies pneumonia(21.05%).The drug resistance degrees of cefaclor,cefuroxime,piperacillin were higher;the drug resistance degrees of amoxicillin clavulanic acid potassium, cefoxitin, ofloxacin,ceftazidime and cefotaxime were lower;they were highly sensitive to imipenem,meropenem.The gram positive bacteria were staphylococcus aureus(8.27% ),streptococcus pneumoniae(4.51% ),staphylococcus haemolyticus(1.5% ).The drug resistance degrees of clindamycin,erythromycin,penicillin were higher;the drug resistance degrees of ofloxacin,tetracycline were lower;they were highly sensitive to vancomycin.Conclusion:Clinicians should pay attention to the pathogenic bacteria detection and drug sensitive test,has cautious and rational drug use.It can improve the curative effect,reduce the resistant strains,and reduce the pain of children.
