CAJ | 학술논문

以磺化硅胶( SSA)为催化剂催化合成尼泊金乙酯,考察SSA用量,反应时间、反应温度和醇酸摩尔比对尼泊金乙酯产率的影响,实验结果表明尼泊金乙酯的最佳反应条件为SSA用量0.3 g,反应时间4 h,反应温度为回流温度,醇酸比为41。尼泊金乙酯的收率为86.7%以SSA作为合成尼泊金酯的催化剂具有产率高,操作简便,可重复使用,具有较好的应用前景。
이광화규효( SSA)위최화제최화합성니박금을지,고찰SSA용량,반응시간、반응온도화순산마이비대니박금을지산솔적영향,실험결과표명니박금을지적최가반응조건위SSA용량0.3 g,반응시간4 h,반응온도위회류온도,순산비위41。니박금을지적수솔위86.7%이SSA작위합성니박금지적최화제구유산솔고,조작간편,가중복사용,구유교호적응용전경。
Silica sulfuric acid was used as the catalyst for synthesis of nipagin ester. The efects of SSA amounts, reaction time, reaction temperature and molar ratio of alcoholto acid on the product yield were investigated. The experimental results showed that the optimum conditions were as follows:reaction time 4 h at reflux temperature, the molar ratio of alcohol to acid 41, the amounts of SSA 0.3 g. The yield of nipagin ester was 86.7%. The synthesis of Nipagin ester using SSA as catalyst, is an easy way with high productivity and repeated utilization, has better application prospect.