中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2015年
5期
35-36
,共2页
冠心病%心房颤动%二联抗栓%华法林%临床疗效%安全性
冠心病%心房顫動%二聯抗栓%華法林%臨床療效%安全性
관심병%심방전동%이련항전%화법림%림상료효%안전성
Coronary heart disease%Atrial fibrillation%Bigeminy antithrombotic%Warfarin%Clinical effect%Safety
目的：评价冠心病合并心房颤动患者的二联抗栓疗效及安全性。方法：选取笔者所在医院2012年4月-2014年1月收治的79例冠心病合并心房颤动患者，按照随机数字表法将其分观察组43例和对照组36例，观察组给予华法林联合氯吡格雷治疗，对照组给予阿司匹林联合氯吡格雷治疗。治疗后对患者进行随访，观察比较两组患者的主要不良事件和心脏不良事件的发生情况。结果：在随访期内，观察组的TIA、缺血性脑卒中、出血及死亡发生率、急性心肌梗死和靶血管血运再次重建发生率均明显低于对照组，差异均有统计学意义(P<0.05)。结论：采用华法林与氯吡格雷联合抗栓治疗冠心病合并心房颤动的临床疗效较高，安全性较为稳定，是一种理想的治疗方式。
目的：評價冠心病閤併心房顫動患者的二聯抗栓療效及安全性。方法：選取筆者所在醫院2012年4月-2014年1月收治的79例冠心病閤併心房顫動患者，按照隨機數字錶法將其分觀察組43例和對照組36例，觀察組給予華法林聯閤氯吡格雷治療，對照組給予阿司匹林聯閤氯吡格雷治療。治療後對患者進行隨訪，觀察比較兩組患者的主要不良事件和心髒不良事件的髮生情況。結果：在隨訪期內，觀察組的TIA、缺血性腦卒中、齣血及死亡髮生率、急性心肌梗死和靶血管血運再次重建髮生率均明顯低于對照組，差異均有統計學意義(P<0.05)。結論：採用華法林與氯吡格雷聯閤抗栓治療冠心病閤併心房顫動的臨床療效較高，安全性較為穩定，是一種理想的治療方式。
목적：평개관심병합병심방전동환자적이련항전료효급안전성。방법：선취필자소재의원2012년4월-2014년1월수치적79례관심병합병심방전동환자，안조수궤수자표법장기분관찰조43례화대조조36례，관찰조급여화법림연합록필격뢰치료，대조조급여아사필림연합록필격뢰치료。치료후대환자진행수방，관찰비교량조환자적주요불량사건화심장불량사건적발생정황。결과：재수방기내，관찰조적TIA、결혈성뇌졸중、출혈급사망발생솔、급성심기경사화파혈관혈운재차중건발생솔균명현저우대조조，차이균유통계학의의(P<0.05)。결론：채용화법림여록필격뢰연합항전치료관심병합병심방전동적림상료효교고，안전성교위은정，시일충이상적치료방식。
Objective:To evaluate the clinical effect and safety evaluation of bigeminy antithrombotic in patients with coronary heart disease complicated with atrial fibrillation.Method:79 cases of coronary heart disease complicated with atrial fibrillation in our hospital from April 2012 to January 2014 were selected,they were divided into the observation group for 43 cases and the control group for 36 cases according to the random number table method.The observation group was given Warfarin combined with Clopidogrel,the control group was given Aspirin combined with Clopidogrel.After treatment the patients were followed up,the occurrence of major adverse events and adverse cardiac events of the two groups were observed and compared. Result:The incidence rate of TIA,ischemic stroke,hemorrhage,death,acute myocardial infarction and target vessel blood supply reconstruction in observation group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Taking Warfarin combined with Clopidogrel in the treatment of coronary heart disease complicated with atrial fibrillation has good effect and the safety is stable,it is an ideal treatment method.
