CAJ | 학술논문

目的：探讨脑梗死后出血性转化的临床特点、发病机制、治疗及预后。方法：回顾性分析笔者所在医院2008年9月-2013年12月收治的67例脑梗死后出血性转化患者的临床资料。结果：脑梗死后出血性转化多发生于脑梗死后3 d~2周内，发病时间早晚与患者预后相关，其发病机制主要与脑血管屏障破坏、缺血再灌注及侧支循环形成相关。本组67例患者均行头颅CT复查证实，经治疗后39例基本愈合，19例好转，6例预后较差，3例死亡。结论：脑梗后出血性转化是脑梗死后常见并发症，其一方面是脑梗死区域血管再通表现，另一方面也对脑梗死预后造成严重后果，应根据发病时间早晚、临床特点及头颅CT表现等的不同，给予不同治疗。
목적：탐토뇌경사후출혈성전화적림상특점、발병궤제、치료급예후。방법：회고성분석필자소재의원2008년9월-2013년12월수치적67례뇌경사후출혈성전화환자적림상자료。결과：뇌경사후출혈성전화다발생우뇌경사후3 d~2주내，발병시간조만여환자예후상관，기발병궤제주요여뇌혈관병장파배、결혈재관주급측지순배형성상관。본조67례환자균행두로CT복사증실，경치료후39례기본유합，19례호전，6례예후교차，3례사망。결론：뇌경후출혈성전화시뇌경사후상견병발증，기일방면시뇌경사구역혈관재통표현，령일방면야대뇌경사예후조성엄중후과，응근거발병시간조만、림상특점급두로CT표현등적불동，급여불동치료。
Objective:To investigate the clinical characteristics,pathogenesis,treatment and prognosis of hemorrhagic transformation after cerebral infarction.Method:The clinical data of 67 patients with hemorrhagic transformation after cerebral infarction admitted to our hospital from September 2008 to December 2013 were retrospectively analyzed.Result:Hemorrhagic transformation after cerebral infarction occurred in 3 d to 2 weeks after cerebral infarction,the onset time of sooner or later related to the prognosis of the patients,its pathogenesis were mainly related to the blood-brain barrier damage,ischemia reperfusion and the formation of collateral circulation.The group of 67 patients underwent head CT scans confirmed that after treatment 39 cases healed,19 cases improved,6 cases with poor prognosis,3 cases of death.Conclusion:Hemorrhagic transformation after cerebral infarction is a common complication after cerebral infarction,on the one hand is cerebral infarction area recanalization performance,on the other hand also cause serious consequences on the prognosis of cerebral infarction,should be based on the different of onset time of sooner or later,clinical characteristics and brain CT manifestations to give different treatment.