中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
4期
61-63,64
,共4页
妊娠%急性肾盂肾炎%流行病学
妊娠%急性腎盂腎炎%流行病學
임신%급성신우신염%류행병학
Pregnancy%Acute pyelonephritis%Epidemiology
目的:分析东莞地区妊娠合并急性肾盂肾炎的流行病学特点。方法:收集2012年1月-2013年12月本院483例妊娠合并急性肾盂肾炎患者的临床资料,统计妊娠期急性肾盂肾炎发病率、症状与合并症、致病菌分布、常见致病菌耐药性和妊娠期急性肾盂肾炎患者的预后。结果:妊娠期急性肾盂肾炎总发病率为3.13%,2012年和2013年发病率分别为2.47%和3.69%。2013年妊娠期急性肾盂肾炎发病率高于2012年,差异有统计学意义(P=0.000)。483例患者中发热(体温超过38.3℃)429例(88.82%)、贫血(血红蛋白低于90 g/L)265例(54.87%)、急性肾功能不全(肌酐升高基础值1.5倍)89例(18.43%)、电解质紊乱58例(12.01%)。392例阳性培养中杆菌、球菌和真菌分别为229株(58.42%)、117株(29.85%)和46株(11.73%),其中最常见的致病菌依次为大肠埃希菌(40.82%)、腐生葡萄球菌(16.58%)、肺炎克雷伯菌(11.22%)、粪肠球菌(8.16%)。2013年真菌感染14.40%高于2012年7.04%,差异有统计学意义(P=0.044)。2013年热带念珠菌检出率8.00%高于2012年1.41%,差异有统计学意义(P=0.013)。大肠埃希菌、腐生葡萄球菌和肺炎克雷伯菌均对常用的A、B类抗生素敏感。妊娠急性肾盂肾炎患者预后较好。结论:东莞地区妊娠合并急性肾盂肾炎发病率较高,真菌感染应引起重视。
目的:分析東莞地區妊娠閤併急性腎盂腎炎的流行病學特點。方法:收集2012年1月-2013年12月本院483例妊娠閤併急性腎盂腎炎患者的臨床資料,統計妊娠期急性腎盂腎炎髮病率、癥狀與閤併癥、緻病菌分佈、常見緻病菌耐藥性和妊娠期急性腎盂腎炎患者的預後。結果:妊娠期急性腎盂腎炎總髮病率為3.13%,2012年和2013年髮病率分彆為2.47%和3.69%。2013年妊娠期急性腎盂腎炎髮病率高于2012年,差異有統計學意義(P=0.000)。483例患者中髮熱(體溫超過38.3℃)429例(88.82%)、貧血(血紅蛋白低于90 g/L)265例(54.87%)、急性腎功能不全(肌酐升高基礎值1.5倍)89例(18.43%)、電解質紊亂58例(12.01%)。392例暘性培養中桿菌、毬菌和真菌分彆為229株(58.42%)、117株(29.85%)和46株(11.73%),其中最常見的緻病菌依次為大腸埃希菌(40.82%)、腐生葡萄毬菌(16.58%)、肺炎剋雷伯菌(11.22%)、糞腸毬菌(8.16%)。2013年真菌感染14.40%高于2012年7.04%,差異有統計學意義(P=0.044)。2013年熱帶唸珠菌檢齣率8.00%高于2012年1.41%,差異有統計學意義(P=0.013)。大腸埃希菌、腐生葡萄毬菌和肺炎剋雷伯菌均對常用的A、B類抗生素敏感。妊娠急性腎盂腎炎患者預後較好。結論:東莞地區妊娠閤併急性腎盂腎炎髮病率較高,真菌感染應引起重視。
목적:분석동완지구임신합병급성신우신염적류행병학특점。방법:수집2012년1월-2013년12월본원483례임신합병급성신우신염환자적림상자료,통계임신기급성신우신염발병솔、증상여합병증、치병균분포、상견치병균내약성화임신기급성신우신염환자적예후。결과:임신기급성신우신염총발병솔위3.13%,2012년화2013년발병솔분별위2.47%화3.69%。2013년임신기급성신우신염발병솔고우2012년,차이유통계학의의(P=0.000)。483례환자중발열(체온초과38.3℃)429례(88.82%)、빈혈(혈홍단백저우90 g/L)265례(54.87%)、급성신공능불전(기항승고기출치1.5배)89례(18.43%)、전해질문란58례(12.01%)。392례양성배양중간균、구균화진균분별위229주(58.42%)、117주(29.85%)화46주(11.73%),기중최상견적치병균의차위대장애희균(40.82%)、부생포도구균(16.58%)、폐염극뢰백균(11.22%)、분장구균(8.16%)。2013년진균감염14.40%고우2012년7.04%,차이유통계학의의(P=0.044)。2013년열대념주균검출솔8.00%고우2012년1.41%,차이유통계학의의(P=0.013)。대장애희균、부생포도구균화폐염극뢰백균균대상용적A、B류항생소민감。임신급성신우신염환자예후교호。결론:동완지구임신합병급성신우신염발병솔교고,진균감염응인기중시。
Objective:To analyze the epidemiologic data of acute pyelonephritis with pregnancy in Dongguan district.Method:483 patients of acute pyelonephritis with pregnancy were enrolled from January 2012 to December 2013.Morbidity of acute pyelonephritis with pregnancy,symptom and complication,spectrum of pathogen,tolerance, prognosis were investigated.Result:Morbidity of acute pyelonephritis with pregnancy was 3.13%,morbidity of acute pyelonephritis with pregnancy in 2013 for 3.69%was significantly higher than that in 2012 for 2.47%,the difference was statistically significant(P=0.000).Symptom and complication included pyrexia>38.3℃were 429 cases for 88.82%, anemia(hemoglobin<90 g/L)were 265 cases for 54.87%,acute kidney dysfunction(baseline creatinine increased 1.5 times)were 89 cases for 18.43%and electrolyte disorder were 58 cases for 12.01%.In 483 were a total of 392 urine cultures were positive,including bacillus were 229 cases accounted for 58.42%,coccus were 117 cases accounted for 29.85%,fungi were 46 cases accounted for 11.73%,the major pathogen were as follows:escherichia coli for 40.82%, staphylococcus saprophyticus for 16.58%,klebsiella pneumonia for 11.22%and enterococcus faecalis for 8.16%.Morbidity of fungal infection in 2013 for 14.40%was significantly higher than that in 2012 for 7.04%,the difference was statistically significant(P=0.044).Detectable rate of candida tropicalis in 2013 for 8.00%was significantly higher than that in 2012 for 1.41%,the difference was statistically significant(P=0.013).Escherichia coli,staphylococcus saprophyticus, klebsiella pneumonia were sensitive to common antibiotics.Pregnancy outcomes in patients with acute pyelonephritis was better.Conclusion:Morbidity of acute pyelonephritis with pregnancy is high.We could pay more attention to fungal infection.