北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2015年
2期
56-56,57
,共2页
老年人%冠心病%阿托伐他汀%临床效果
老年人%冠心病%阿託伐他汀%臨床效果
노년인%관심병%아탁벌타정%림상효과
The elderly%Coronary heart disease%Atorvastatin%Clinical effect
目的：观察老年冠心病患者采用不同剂量阿托伐他汀治疗的临床效果。方法：选取我院2013年1月～2014年6月收治的152例接受不同剂量阿托伐他汀治疗的老年冠心病患者为研究对象，随机分成两组，对照组治疗剂量为10mg，实验组治疗剂量为20mg，对比两组临床治疗效果。结果：实验组TG（mmol/L：1.11±0.42 vs 1.37±0.46）、LDL-C（mmol/L：1.05±0.48 vs 1.64±0.41）、TC （mmol/L：3.28±0.64 vs 4.41±0.63）明显低于对照组，HDL-C水平（mmol/L：1.23±0.38 vs 1.11±0.40）显著高于对照组，且窦性心律维持率（17.10％vs36.84％）高于对照组，差异显著（P＜0.05）。结论：高剂量阿托伐他汀治疗老年血脂正常冠心病患者临床疗效确切，值得临床推广。
目的：觀察老年冠心病患者採用不同劑量阿託伐他汀治療的臨床效果。方法：選取我院2013年1月～2014年6月收治的152例接受不同劑量阿託伐他汀治療的老年冠心病患者為研究對象，隨機分成兩組，對照組治療劑量為10mg，實驗組治療劑量為20mg，對比兩組臨床治療效果。結果：實驗組TG（mmol/L：1.11±0.42 vs 1.37±0.46）、LDL-C（mmol/L：1.05±0.48 vs 1.64±0.41）、TC （mmol/L：3.28±0.64 vs 4.41±0.63）明顯低于對照組，HDL-C水平（mmol/L：1.23±0.38 vs 1.11±0.40）顯著高于對照組，且竇性心律維持率（17.10％vs36.84％）高于對照組，差異顯著（P＜0.05）。結論：高劑量阿託伐他汀治療老年血脂正常冠心病患者臨床療效確切，值得臨床推廣。
목적：관찰노년관심병환자채용불동제량아탁벌타정치료적림상효과。방법：선취아원2013년1월～2014년6월수치적152례접수불동제량아탁벌타정치료적노년관심병환자위연구대상，수궤분성량조，대조조치료제량위10mg，실험조치료제량위20mg，대비량조림상치료효과。결과：실험조TG（mmol/L：1.11±0.42 vs 1.37±0.46）、LDL-C（mmol/L：1.05±0.48 vs 1.64±0.41）、TC （mmol/L：3.28±0.64 vs 4.41±0.63）명현저우대조조，HDL-C수평（mmol/L：1.23±0.38 vs 1.11±0.40）현저고우대조조，차두성심률유지솔（17.10％vs36.84％）고우대조조，차이현저（P＜0.05）。결론：고제량아탁벌타정치료노년혈지정상관심병환자림상료효학절，치득림상추엄。
Objective:To observe the clinical effect of different doses of atorvastatin on elderly patients with coronary heart disease. Methods:This article made old blood lipids in patients with coronary heart disease who has adopted different doses of atorvastatin treatment in our hospital in January 2013~June 2014 as the research objects, we randomly selected 152 cases and they were divided into two groups. The control group was given a therapeutic dose of 10mg, the experimental was given a therapeutic dose of 20mg, and then compared two groups of clinical outcomes. Results:In experimental group, TG (mmol/L:1.11±0.42 vs 1.37±0.46),LDL-C(mmol/L:1.05±0.48 vs 1.64±0.41), TC (mmol/L:3.28± 0.64 vs 4.41±0.63) was significantly lower than the control group, the level of HDL-C (mmol/L:1.23 ± 0.38 vs 1.11 ±0.40)was significantly higher than that of control group, and the maintenance rate of sinus heart rate (17.10%vs36.84%) was higher than that of control group, difference was significant(P<0.05). Conclusion:There is a significant clinical effect that high-dose atorvastatin therapy in old blood lipids in patients with coronary heart disease, and it is worthy of positive promotion and application.
